中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
9期
1400-1401,1403
,共3页
维持性血液透析%老年患者%死亡原因%C-反应蛋白%血浆白蛋白
維持性血液透析%老年患者%死亡原因%C-反應蛋白%血漿白蛋白
유지성혈액투석%노년환자%사망원인%C-반응단백%혈장백단백
Maintenance hemodialysis%Elderly patient%Cause of death%C-reactive protein%Serum albumin
目的:分析老年维持性血液透析(maintenance hemodialysis,MHD)患者主要死亡原因及C-反应蛋白(C-reactive protein,CRP)、血浆白蛋白(serum albumin,ALB)变化情况。方法:本研究纳入2009年8月至2012年6月在我院死亡,且60岁以上老年MHD患者21例[其中男性14例,女性7例。平均年龄(70.17±10.05岁)],回顾分析其一般资料及死亡前3个月、6个月CRP、ALB水平及随机选取同期非死亡老年MHD患者20例(男12例,女8例,平均年龄68.61±11.42岁)调查其相应化验指标并做对比分析。结果:心、脑血管病为第一位死因,感染性疾患占第二位。多数患者透析生存年限小于5年。死亡患者CRP水平高于非死亡患者[15.75±4.74 VS 7.64±4.87),P<0.05],ALB低于非死亡患者[(37.65±7.91 VS 35.89±4.39),P<0.05]。结论:老年MHD患者死亡率较高,存在慢性炎症状态及营养不良。
目的:分析老年維持性血液透析(maintenance hemodialysis,MHD)患者主要死亡原因及C-反應蛋白(C-reactive protein,CRP)、血漿白蛋白(serum albumin,ALB)變化情況。方法:本研究納入2009年8月至2012年6月在我院死亡,且60歲以上老年MHD患者21例[其中男性14例,女性7例。平均年齡(70.17±10.05歲)],迴顧分析其一般資料及死亡前3箇月、6箇月CRP、ALB水平及隨機選取同期非死亡老年MHD患者20例(男12例,女8例,平均年齡68.61±11.42歲)調查其相應化驗指標併做對比分析。結果:心、腦血管病為第一位死因,感染性疾患佔第二位。多數患者透析生存年限小于5年。死亡患者CRP水平高于非死亡患者[15.75±4.74 VS 7.64±4.87),P<0.05],ALB低于非死亡患者[(37.65±7.91 VS 35.89±4.39),P<0.05]。結論:老年MHD患者死亡率較高,存在慢性炎癥狀態及營養不良。
목적:분석노년유지성혈액투석(maintenance hemodialysis,MHD)환자주요사망원인급C-반응단백(C-reactive protein,CRP)、혈장백단백(serum albumin,ALB)변화정황。방법:본연구납입2009년8월지2012년6월재아원사망,차60세이상노년MHD환자21례[기중남성14례,녀성7례。평균년령(70.17±10.05세)],회고분석기일반자료급사망전3개월、6개월CRP、ALB수평급수궤선취동기비사망노년MHD환자20례(남12례,녀8례,평균년령68.61±11.42세)조사기상응화험지표병주대비분석。결과:심、뇌혈관병위제일위사인,감염성질환점제이위。다수환자투석생존년한소우5년。사망환자CRP수평고우비사망환자[15.75±4.74 VS 7.64±4.87),P<0.05],ALB저우비사망환자[(37.65±7.91 VS 35.89±4.39),P<0.05]。결론:노년MHD환자사망솔교고,존재만성염증상태급영양불량。
Objectives:To investigate the causes of death in elderly maintenance hemodialysis(MHD) patients. And to analyse the variation of the concentration of C-reactive protein(CRP) and serum albumin(ALB) in those patients.Methods:There were 21 patients [14 men, 7 women ,mean age (70.17±10.05)]recruited in this study. They died in our Blood purification Center from Aug 2009 to Jun 2012.And we chose 20 patients [12 men,8 women,mean age (68.61±11.42)]randomly as the control group treated at the same period. We compared the concentration of CRP and ALB at the time of 3 and 6 month before they died, and compared these items between the two groups.Results:Cardiocerebral vascular disease are the top 1 cause to the death of MHD patients. Infection disease was next it. Most people died in five years after dialysis treatment. The concentration of CRP in death group was higher than that in control group(15.75±4.74 VS 7.64±4.87,P<0.05). And the ALB concentration was just the reverse(37.65±7.91 VS 35.89±4.39,P<0.05).Conclusion:The death rate was high in elderly MHD patients.Chronic inflammation and malnutrition were prevalent in these patients.