中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
9期
1510-1511
,共2页
卡前列素氨丁三醇%产后出血%高危因素
卡前列素氨丁三醇%產後齣血%高危因素
잡전렬소안정삼순%산후출혈%고위인소
Carboprost tromethamine%Postpartum hemorrhage%Risk factors
目的：探讨了卡前列素氨丁三醇治疗产后出血高危因素孕妇的疗效观察。方法：回顾性分析我院2010年2月～2013年2月收治的80例产后出血高危因素剖宫产产妇的临床资料，随机分为对照组和观察组，观察组产妇在常规治疗的基础上给予宫体注射卡前列素氨丁三醇治疗，对照组产妇在常规治疗的基础上给予米索前列醇、垂体后叶素宫体注射治疗。结果：产后2h、4h出血量比较，观察组均显著低于对照组，差异有显著性意义(P<0.05)；观察组产后出血发生率为12.5%，对照组产后出血发生率为31.91%，两组对比统计学有显著性差异(P<0.05)；观察组止血时间显著低于对照组，差异有显著性意义(P<0.05)；观察组输血患者2例(5%)，输血患者10例(25%)，观察组显著低于对照组，两组差异有显著性意义(P<0.05)；观察组没有患者行子宫切除术，对照组有2例行子宫切除术，统计学均有显著性差异(P<0.05)。观察组不良反应3例，对照组2例。结论：预防性宫体注射卡前列素氨丁三醇在产后出血高危因素孕妇剖宫产术中能明显减少产后出血量，降低产后出血发生率和输血率，缩短止血时间，减少近远期并发症，值得临床推广。
目的：探討瞭卡前列素氨丁三醇治療產後齣血高危因素孕婦的療效觀察。方法：迴顧性分析我院2010年2月～2013年2月收治的80例產後齣血高危因素剖宮產產婦的臨床資料，隨機分為對照組和觀察組，觀察組產婦在常規治療的基礎上給予宮體註射卡前列素氨丁三醇治療，對照組產婦在常規治療的基礎上給予米索前列醇、垂體後葉素宮體註射治療。結果：產後2h、4h齣血量比較，觀察組均顯著低于對照組，差異有顯著性意義(P<0.05)；觀察組產後齣血髮生率為12.5%，對照組產後齣血髮生率為31.91%，兩組對比統計學有顯著性差異(P<0.05)；觀察組止血時間顯著低于對照組，差異有顯著性意義(P<0.05)；觀察組輸血患者2例(5%)，輸血患者10例(25%)，觀察組顯著低于對照組，兩組差異有顯著性意義(P<0.05)；觀察組沒有患者行子宮切除術，對照組有2例行子宮切除術，統計學均有顯著性差異(P<0.05)。觀察組不良反應3例，對照組2例。結論：預防性宮體註射卡前列素氨丁三醇在產後齣血高危因素孕婦剖宮產術中能明顯減少產後齣血量，降低產後齣血髮生率和輸血率，縮短止血時間，減少近遠期併髮癥，值得臨床推廣。
목적：탐토료잡전렬소안정삼순치료산후출혈고위인소잉부적료효관찰。방법：회고성분석아원2010년2월～2013년2월수치적80례산후출혈고위인소부궁산산부적림상자료，수궤분위대조조화관찰조，관찰조산부재상규치료적기출상급여궁체주사잡전렬소안정삼순치료，대조조산부재상규치료적기출상급여미색전렬순、수체후협소궁체주사치료。결과：산후2h、4h출혈량비교，관찰조균현저저우대조조，차이유현저성의의(P<0.05)；관찰조산후출혈발생솔위12.5%，대조조산후출혈발생솔위31.91%，량조대비통계학유현저성차이(P<0.05)；관찰조지혈시간현저저우대조조，차이유현저성의의(P<0.05)；관찰조수혈환자2례(5%)，수혈환자10례(25%)，관찰조현저저우대조조，량조차이유현저성의의(P<0.05)；관찰조몰유환자행자궁절제술，대조조유2례행자궁절제술，통계학균유현저성차이(P<0.05)。관찰조불량반응3례，대조조2례。결론：예방성궁체주사잡전렬소안정삼순재산후출혈고위인소잉부부궁산술중능명현감소산후출혈량，강저산후출혈발생솔화수혈솔，축단지혈시간，감소근원기병발증，치득림상추엄。
Objective:To investigate the carboprost tromethamine in the treatment of postpartum hemorrhage as risk factors in pregnant wonmen.Methods:A retrospective analysis of 80 cases of postpartum hemorrhage risk factors for cesarean section performed clinical data in our hospital from February 2010 to February 2013,were randomly divided into control group and observation group,were observed in the conventional treatment group,the observation group of delivery women on the basis of conventional therapy for uterine body injected by carboprost trometamol, control group delivery women on the basis of routine treatment, given misoprostol, pituitrin injection in the treatment of uterine body.Results:Postpartum 2h, 4h amount of bleeding in the observation group were significantly lower than the control group, the difference was significant (P<0.05);observation group postpartum hemorrhage rate was 12.5%in the control group was 31.91%of postpartum hemorrhage, between two groups was statistically significant difference (P<0.05);observation group was significantly lower than the control bleeding group, the difference was statistically significant (P<0.05);observation group:2 patients transfusion (5%),blood transfusion in patients 10 cases (25%) in the observation group was significantly lower than the control group, the difference was statistically significant (P<0.05);observation group underwent hysterectomy without the control group, two routine hysterectomy, were statistically significant difference (P<0.05). Adverse reactions observed in 3 cases,2 cases of the control group. Conclusion:The prevention of intrauterine injection of carboprost trometamol in the risk factors of postpartum hemorrhage in cesarean section surgery can significantly reduce the amount of postpartum hemorrhage, reducing the incidence rate of postpartum hemorrhage and blood transfusion rate, shorten the bleeding time, reduce the complication, is worth the clinical promotion.
