CAJ | 학술논문

目的：对比观察依达拉奉联合神经节苷脂治疗急性脑梗死临床效果及安全性，为临床用药作出指导。方法：选择我院自2010年1月至2012年1月收治的67例急性脑梗死患者为研究对象，随机分为两组。实验组给予依达拉奉联合单唾液酸四己糖神经节苷脂治疗，对照组仅予以单唾液酸四己糖神经节苷脂，对比观察两组患者治疗后NHISS评分情况、临床疗效情况。结果：两组患者治疗前NIHSS评分无统计学差异(P>0.05)，两组患者治疗前后NIHSS评分均有统计学差异(P<0.05)，两组患者NIHSS评分差值比较具有统计学意义(P<0.05)。实验组显效率为36.36%，对照组显效率为20.59%，两组比较具有显著差异(P<0.05)，实验组有效率为69.70%，对照组有效率为40.09%，两组比较具有统计学差异(P<0.05)。结论：依达拉奉联合神经节苷脂和单独使用神经节苷脂治疗急性脑梗死临床效果均好，但是联合用药对患者NHISS评分影响更大，值得临床广泛推广。
목적：대비관찰의체랍봉연합신경절감지치료급성뇌경사림상효과급안전성，위림상용약작출지도。방법：선택아원자2010년1월지2012년1월수치적67례급성뇌경사환자위연구대상，수궤분위량조。실험조급여의체랍봉연합단타액산사기당신경절감지치료，대조조부여이단타액산사기당신경절감지，대비관찰량조환자치료후NHISS평분정황、림상료효정황。결과：량조환자치료전NIHSS평분무통계학차이(P>0.05)，량조환자치료전후NIHSS평분균유통계학차이(P<0.05)，량조환자NIHSS평분차치비교구유통계학의의(P<0.05)。실험조현효솔위36.36%，대조조현효솔위20.59%，량조비교구유현저차이(P<0.05)，실험조유효솔위69.70%，대조조유효솔위40.09%，량조비교구유통계학차이(P<0.05)。결론：의체랍봉연합신경절감지화단독사용신경절감지치료급성뇌경사림상효과균호，단시연합용약대환자NHISS평분영향경대，치득림상엄범추엄。
Objective:To compare clinical effect and safety of edaravone joint ganglioside treatment of acute cerebral infarction ,for clinical guidance.Methods:Slected 67 patients with acute cerebral infarction patients admitted to our hospital from January 2010 to January 2012 as the research object, randomly divided them into two groups. Experimental group were given edaravone joint ganglioside treatment, the control group were given ganglioside , compared the NHISS score and the clinical efficacy of two groups after received treatment.Results:The NIHSS score of two groups of patients before treatment had no significant difference (P>0.05), NIHSS score in both of the two groups after treatment had statistically significant than the score before received treatment(P<0.05), the NIHSS score difference between two groups of patients had statistically significant (P<0.05). Experimental group Significant efficiency rate is 36.36%, while the control group was 20.59%,which were significant different (P<0.05), the effective rate of experimental group was 69.70%, while the control group was 40.09%, which were statistically different (P<0.05).Conclusion:Both of Edaravone joint ganglioside and ganglioside used alone for acute cerebral infarction have good clinical effects , but the the the United medication of patients has greater impact in NHISS score , which is worthy of clinical widely.