CAJ | 학술논문

背景与目的纵隔淋巴瘤或右上肺癌是导致上腔静脉阻塞综合征（superior vena cava obstruction syn-drome, SVCOS）的常见病因。气管腔内超声引导针吸活检术（endobronchial ultrasound-guided transbronchial needle aspiration, EBUS-TBNA）在纵隔占位疾病的诊断方面，与外科手术相当。本研究旨在探讨全麻状态下EBUS-TBNA在SVCOS临床病因诊断中的安全性及可行性。方法2012年6月-2013年6月25例伴有SVCOS全麻状态下接受EBUS-TBNA的患者，其中男16例，女9例；年龄33岁-76岁，中位62.5岁。结果24例病理学证实为恶性肿瘤，确诊率为96.0%（24/25），1例未能获得明确病理诊断；所有患者均未出现与操作相关的并发症，包括大量出血与气胸。结论对伴有SVCOS的患者，全麻状态下EBUS-TBNA仍是一种确诊率高、安全可靠的微创检查方法，可作为其他手段不能明确病理诊断的常规检查。
배경여목적종격림파류혹우상폐암시도치상강정맥조새종합정（superior vena cava obstruction syn-drome, SVCOS）적상견병인。기관강내초성인도침흡활검술（endobronchial ultrasound-guided transbronchial needle aspiration, EBUS-TBNA）재종격점위질병적진단방면，여외과수술상당。본연구지재탐토전마상태하EBUS-TBNA재SVCOS림상병인진단중적안전성급가행성。방법2012년6월-2013년6월25례반유SVCOS전마상태하접수EBUS-TBNA적환자，기중남16례，녀9례；년령33세-76세，중위62.5세。결과24례병이학증실위악성종류，학진솔위96.0%（24/25），1례미능획득명학병리진단；소유환자균미출현여조작상관적병발증，포괄대량출혈여기흉。결론대반유SVCOS적환자，전마상태하EBUS-TBNA잉시일충학진솔고、안전가고적미창검사방법，가작위기타수단불능명학병리진단적상규검사。
Background and objective Mediastinal lymphoma or right upper lung cancer is a common cause of superior vena cava obstruction syndrome (SVCOS). Endobronchial ultrasound-guided needle aspiration (EBUS-TBNA) biopsy is applied for the diagnosis of mediastinal mass disease. hTe aim of this study is to explore the safety and feasibility of EBUS-TBNA biopsy under general anesthesia for the clinical diagnosis of SVCOS. Methods Twenty-ifve cases of SVCOS re-ceived EBUS-TBNA under general anesthesia between June 2012 and June 2013. hTe group consisted of 16 male and 9 female patients aged 33 years to 76 years, with a median age of 62.5. Results Twenty-four cases were conifrmed to be of malignant pathology, and one case failed to yield a clear pathological diagnosis. No patient experienced any complications related to the operation, such as heavy bleeding and pneumothorax. Conclusion For patients presenting with SVCOS, EBUS-TBNA under general anesthesia is a safe and reliable inspection method of high diagnostic yield. hTis method can be used for routine exami-nation when other means cannot obtain clear pathological diagnosis.