CAJ | 학술논문

背景与目的近20年来，中国肺癌的发病水平呈明显上升趋势，但其性别和城乡发病差异以及平均发病年龄的变化趋势并不清楚。本研究将对1989年-2008年中国肺癌发病率在性别、城乡差异和平均发病年龄的变化趋势进行分析。方法利用全国1989年-2008年肿瘤登记地区的肺癌发病数据和人口数据，按照不同性别、不同地区（城乡）分层，运用Poisson回归模型和线性回归模型，分析发病率的性别比值、城乡比值和平均发病年龄的变化特征。结果和1989年相比，2008年肺癌发病率男女比值由2.47降低到了2.28，城乡比值由2.07下降到了1.14，男性平均发病年龄由65.32岁升高到了67.87岁，女性平均发病年龄由65.14岁升高到了68.05岁。肺癌发病的男女差异和城乡差别逐渐缩小，平均发病年龄逐年升高，变化趋势均有统计学意义。结论近20年，中国肺癌发病的性别和城乡差异明显缩小，发病年龄趋于老龄化，应针对肺癌发病现状开展更有效的防治研究工作。
배경여목적근20년래，중국폐암적발병수평정명현상승추세，단기성별화성향발병차이이급평균발병년령적변화추세병불청초。본연구장대1989년-2008년중국폐암발병솔재성별、성향차이화평균발병년령적변화추세진행분석。방법이용전국1989년-2008년종류등기지구적폐암발병수거화인구수거，안조불동성별、불동지구（성향）분층，운용Poisson회귀모형화선성회귀모형，분석발병솔적성별비치、성향비치화평균발병년령적변화특정。결과화1989년상비，2008년폐암발병솔남녀비치유2.47강저도료2.28，성향비치유2.07하강도료1.14，남성평균발병년령유65.32세승고도료67.87세，녀성평균발병년령유65.14세승고도료68.05세。폐암발병적남녀차이화성향차별축점축소，평균발병년령축년승고，변화추세균유통계학의의。결론근20년，중국폐암발병적성별화성향차이명현축소，발병년령추우노령화，응침대폐암발병현상개전경유효적방치연구공작。
Background and objective hTe lung cancer incidence was signiifcantly increased in the past two de-cades in China. But the secular trend of lung cancer incidence difference between gender (male and female), area (urban and rural) and average age was not clear. hTe aim of this study is to analyze the trend of lung cancer incidence rate ratio between gender, area and average age in China during 1989-2008, and provide some inspiration for lung cancer prevention and control activities. Methods Cancer registry data and population data in China from 1989 to 2008 were collected by the National Cancer Registration Center. Stratiifed for gender and area, Poisson regression model was used to estimate annual lung cancer incidence rate ratio between male and female, urban and rural areas. hTe average age of lung cancer incidence was calculated. Linear regression was used to model the trend of annual incidence rate ratio and average age over time. Results Incidence rate ratios of lung cancer between male and female, urban and rural areas were signiifcantly decreased from 2.47 and 2.07 to 2.28 and 1.14 during 1989-2008, respectively. Meanwhile, the average age of lung cancer incidence among male and female dramati-cally increased from 65.32 and 65.14 to 67.87 and 68.05, respectively. Conclusion hTe difference of lung cancer incidence between male and female, urban and rural areas remarkably decreased from 1989 to 2008. hTe average age of lung cancer oc-currence gradually increased. Researches, prevention and control activities on lung cancer with consideration of new incidence pattern should be strengthened.