CAJ | 학술논문

在许多的生物医学和工程研究中，多类型复发事件的间隔时间数据是很常见的。众所周知，比例危险率模型在一些情况下不能很好拟合生存数据。本文，在多类型复发事件的间隔时间数据下，我们利用可加危险率模型来研究协变量对生存时间的影响程度。我们采用估计方程方法获得回归系数和基准累积危险率函数估计。并且，我们建立了所提估计的渐近分布。
재허다적생물의학화공정연구중，다류형복발사건적간격시간수거시흔상견적。음소주지，비례위험솔모형재일사정황하불능흔호의합생존수거。본문，재다류형복발사건적간격시간수거하，아문이용가가위험솔모형래연구협변량대생존시간적영향정도。아문채용고계방정방법획득회귀계수화기준루적위험솔함수고계。병차，아문건립료소제고계적점근분포。
In many biomedical and engineering studies, recurrent event data and gap times between successive events are common and often more than one type of recurrent events is of interest. It is well known that the proportional hazards model may not be appropriate for fitting survival times in some settings. In the paper, we consider an additive hazards model for multiple type recurrent gap times data to assess the effect of covariates. For inferences about regression coe?cients and baseline cumulative hazard functions, an estimating equation approach is developed. Furthermore, we establish asymptotic properties of the proposed estimators.