北京医学
北京醫學
북경의학
BEIJING MEDICAL JOURNAL
2014年
5期
380-383
,共4页
胶质瘤%转移瘤%磁共振%灌注加权成像%磁敏感加权成像
膠質瘤%轉移瘤%磁共振%灌註加權成像%磁敏感加權成像
효질류%전이류%자공진%관주가권성상%자민감가권성상
Glioma%Metastatic tumor%MR%Perfusion-weighted imaging (PWI)%Susceptibility-weighted imaging (SWI)
目的：探讨灌注加权成像(PWI)、磁敏感加权成像（SWI）在高级别脑胶质瘤和单发脑转移瘤鉴别诊断中的应用价值。方法对术前进行过磁共振PWI与SWI检查并经病理证实的16例高级别脑胶质瘤与11例单发脑转移瘤进行回顾性分析，测量肿瘤实质区与周围水肿区的rCBV值，并以肿瘤SWI图像中低信号程度对两种肿瘤进行评分分析。结果16例高级别脑胶质瘤与11例单发脑转移瘤的肿瘤实质区 rCBV 值分别为9.87±2.76和10.97±2.12，差异无统计学意义（P＞0.05）；肿瘤周围水肿区rCBV值分别为1.99±0.50和1.12±0.23，差异有统计学意义（P＜0.05）。高级别脑胶质瘤组SWI低信号评分高于单发脑转移瘤组，以非参数Mann-Whitney U检验进行统计学分析，差异有统计学意义（P＜0.05）。结论磁共振PWI及SWI有助于显示肿瘤及瘤周组织细微结构，对高级别脑胶质瘤和单发脑转移瘤的鉴别诊断有临床应用价值。
目的：探討灌註加權成像(PWI)、磁敏感加權成像（SWI）在高級彆腦膠質瘤和單髮腦轉移瘤鑒彆診斷中的應用價值。方法對術前進行過磁共振PWI與SWI檢查併經病理證實的16例高級彆腦膠質瘤與11例單髮腦轉移瘤進行迴顧性分析，測量腫瘤實質區與週圍水腫區的rCBV值，併以腫瘤SWI圖像中低信號程度對兩種腫瘤進行評分分析。結果16例高級彆腦膠質瘤與11例單髮腦轉移瘤的腫瘤實質區 rCBV 值分彆為9.87±2.76和10.97±2.12，差異無統計學意義（P＞0.05）；腫瘤週圍水腫區rCBV值分彆為1.99±0.50和1.12±0.23，差異有統計學意義（P＜0.05）。高級彆腦膠質瘤組SWI低信號評分高于單髮腦轉移瘤組，以非參數Mann-Whitney U檢驗進行統計學分析，差異有統計學意義（P＜0.05）。結論磁共振PWI及SWI有助于顯示腫瘤及瘤週組織細微結構，對高級彆腦膠質瘤和單髮腦轉移瘤的鑒彆診斷有臨床應用價值。
목적：탐토관주가권성상(PWI)、자민감가권성상（SWI）재고급별뇌효질류화단발뇌전이류감별진단중적응용개치。방법대술전진행과자공진PWI여SWI검사병경병리증실적16례고급별뇌효질류여11례단발뇌전이류진행회고성분석，측량종류실질구여주위수종구적rCBV치，병이종류SWI도상중저신호정도대량충종류진행평분분석。결과16례고급별뇌효질류여11례단발뇌전이류적종류실질구 rCBV 치분별위9.87±2.76화10.97±2.12，차이무통계학의의（P＞0.05）；종류주위수종구rCBV치분별위1.99±0.50화1.12±0.23，차이유통계학의의（P＜0.05）。고급별뇌효질류조SWI저신호평분고우단발뇌전이류조，이비삼수Mann-Whitney U검험진행통계학분석，차이유통계학의의（P＜0.05）。결론자공진PWI급SWI유조우현시종류급류주조직세미결구，대고급별뇌효질류화단발뇌전이류적감별진단유림상응용개치。
Objective To explore the value of MR perfusion-weighted imaging (PWI) and susceptibility-weighted imaging (SWI) in the differentiation of high-grade gliomas from solitary cerebral metastatic tumors. Methods Sixteen cases of high-grade gliomas and 11 cases of solitary cerebral metastatic tumors underwent conventional MR imaging, SWI and PWI before surgical resection or stereotactic biopsy were analyzed retrospectively. The rCBV value of all cases in tumor parenchyma and peritumoral brain edema (PTBE) were measured. All tumors were scored according to the low signal levels in the SWI images. Results The average rCBV value of 16 cases of high-grade gliomas and 11 cases of solitary cerebral metastatic tumors were 9.87 ±2.76, 10.97 ±2.12 in tumor parenchyma and 1.99 ±0.50, 1.12 ±0.23 in PTBE respectively. The rCBV value between high-grade gliomas and solitary cerebral metastatic tumors were not statistically different in tumor parenchyma (P> 0.05), while that was statistical significant in PTBE (P< 0.05). According to the low signal levels, the scores of high-grade gliomas in the SWI images were higher than those of the solitary cerebral metastatic tumors by non-parametric Mann-Whitney U test (P< 0.05). Conclusion MR PWI and SWI are potential tools in the differentiation of high-grade gliomas from solitary cerebral metastatic tumors by depicting the microscopic structures of tumors and peritumoral areas.
