CAJ | 학술논문

目的了解佳木斯大学附属第一医院鲍曼不动杆菌的分布特征及耐药情况。方法常规方法分离培养鉴定，K-B法做药敏分析。结果鲍曼不动杆菌最多见于痰液标本，占62．0％（98/158），其次是脓液及分泌物标本，占14．6％（23/158）；鲍曼不动杆菌为院内感染，呼吸内科分布最多，占33．5％（53/158），其次是神经内科、重症监护病房和烧伤科。在18种抗菌药物中，碳青霉烯类药物亚胺培南的耐药率最低，为17．1％，美罗培南耐药率为21．5％，其他抗菌药物的耐药率均大于40．0％。结论鲍曼不动杆菌为医院感染中重要的条件致病菌，且耐药率较高，临床医务人员应根据药敏试验结果合理选择抗菌药物，定期进行耐药检测，以便及时有效地控制感染，减少鲍曼不动杆菌耐药菌株的产生。
목적료해가목사대학부속제일의원포만불동간균적분포특정급내약정황。방법상규방법분리배양감정，K-B법주약민분석。결과포만불동간균최다견우담액표본，점62．0％（98/158），기차시농액급분비물표본，점14．6％（23/158）；포만불동간균위원내감염，호흡내과분포최다，점33．5％（53/158），기차시신경내과、중증감호병방화소상과。재18충항균약물중，탄청매희류약물아알배남적내약솔최저，위17．1％，미라배남내약솔위21．5％，기타항균약물적내약솔균대우40．0％。결론포만불동간균위의원감염중중요적조건치병균，차내약솔교고，림상의무인원응근거약민시험결과합리선택항균약물，정기진행내약검측，이편급시유효지공제감염，감소포만불동간균내약균주적산생。
Objective To investigate clinical distribution and drug resistance of Acinetobacter baumannii in The First Hospital Affiliated to Jiamusi University .Methods Bacteria culture and identification were adopted by conventional method .Kirby-bauer method was used as drug sensitive test .Results Acinetobacter baumannii in spu-tum specimens up to 62 .0% (98/158) ,followed by pus and secretion samples of 14 .6% (23/158);Acinetobacter baumannii for nosocomial infection ,in the department of respiratory ,Acinetobacter baumannii distribution for a max-imum of 33 .5% (53/158) ,followed by the departments of neurology ,intensive care unit ,burns deparbment .In 18 kinds of antibacterials ,the resistance rate of imipenem in carbapenems was the lowest (17 .1% ) ,the resistant rute of meropenem was 21 .5% ,other antimicrobial resistance rates were higher than 40 .0% .Conclusion Acinetobacter baumannii is the major opportunistic pathogenic bacteria in nosocomial infection ,and drug resistance rate is higher . Clinicians should rationally choose antibacterials according to susceptibility test results ,regular resistance test ,in or-der to effectively control the infection ,reduce the resistant strains of Acinetobacter baumannii .