CAJ | 학술논문

目的探讨血清超敏C反应蛋白（hsCRP）水平评估急性冠脉综合征患者预后的可行性。方法对127例急性冠脉综合征患者入院当天测定血浆hsCRP水平，根据血浆hsCRP水平分为3组：≤10.0 mg/L组，10.1～20.0 mg/L组，＞20.0 mg/L组。随访ACS患者住院期间、30 d以及3个月死亡事件以及主要心脏不良事件（MACE)的发生情况。结果hsCRP水平与ACS患者的临床事件的发生率密切相关，CRP水平预测30 d、3个月的死亡率和MACE差异有统计学意义。结论hsCRP水平可预测短期的病死率和MACE发生率，对判断ACS患者的预后有重要价值。
목적탐토혈청초민C반응단백（hsCRP）수평평고급성관맥종합정환자예후적가행성。방법대127례급성관맥종합정환자입원당천측정혈장hsCRP수평，근거혈장hsCRP수평분위3조：≤10.0 mg/L조，10.1～20.0 mg/L조，＞20.0 mg/L조。수방ACS환자주원기간、30 d이급3개월사망사건이급주요심장불량사건（MACE)적발생정황。결과hsCRP수평여ACS환자적림상사건적발생솔밀절상관，CRP수평예측30 d、3개월적사망솔화MACE차이유통계학의의。결론hsCRP수평가예측단기적병사솔화MACE발생솔，대판단ACS환자적예후유중요개치。
Objective To evaluate the prognostic value of plasma high sensitivity C-reactive (hsCRP) protein in patients with acute coronary syndrome. Methods 127 patients with ACS were adopted in the study.According to the hsCRP levels,patients were divided into 3 groups (hsCRP≤10.0mg/L,10.1~20.0mg/L,>20.0mg/L).Measured the risk for major adverse cardiac events (MACE) at 30 days and 3 months were analyzed. Results Mortality and MACE incidence increased significantly in the patients with high hsCRP levels.Plasma hsCRP level predicted 30-day and 3-month mortality and MACE incidence independent of age,gender,hypertension,smoking,hyperlipimia and diabetes. Conclusion Plasma hsCRP is a good predictor for mortality and MACE incidence in ACS patients.