CAJ | 학술논문

目的初步评价金匮肾气丸治疗牙周病的临床疗效。方法选取120例牙周病病例，经中医辩证诊断为肾气亏损；随机分为两组各60例，A组采用中医辨证治疗，进行一次全口龈上、龈下超声波洁治后，先以金匮肾气丸汤剂每日1剂，2次/d，煎服2周，后以丸剂桂附地黄丸口服，每次8丸，2次/d，2周为一疗程，3个疗程结束后统计疗效。B组单纯进行一次全口龈上、龈下超声波洁治。疗效测定分别于治疗前(基线)、疗程结束后4周、12周复诊分别检查记录每个受检位点的①菌斑指数(plaque index，PLI)、②龈沟出血指数(sulcus bleeding index，SBI)、③牙周探诊深度(periodontal probing depth，PD)、④附着丧失(attachment loss，AL)、⑤探诊出血(bleeding onp robin，BOP)牙周检测临床指标。结果 A组疗程结束后4周、12周的PLI、SBI、PD、AL、BOP疗效测定分别与治疗前(基线)对比明显改善，差异有统计学意义；B组差异无统计学意义；A组与B组比较，差异有统计学意义。结论金匮肾气丸治疗牙周病短期疗效良好，但长期疗效仍有待观察研究。
목적초보평개금궤신기환치료아주병적림상료효。방법선취120례아주병병례，경중의변증진단위신기우손；수궤분위량조각60례，A조채용중의변증치료，진행일차전구간상、간하초성파길치후，선이금궤신기환탕제매일1제，2차/d，전복2주，후이환제계부지황환구복，매차8환，2차/d，2주위일료정，3개료정결속후통계료효。B조단순진행일차전구간상、간하초성파길치。료효측정분별우치료전(기선)、료정결속후4주、12주복진분별검사기록매개수검위점적①균반지수(plaque index，PLI)、②간구출혈지수(sulcus bleeding index，SBI)、③아주탐진심도(periodontal probing depth，PD)、④부착상실(attachment loss，AL)、⑤탐진출혈(bleeding onp robin，BOP)아주검측림상지표。결과 A조료정결속후4주、12주적PLI、SBI、PD、AL、BOP료효측정분별여치료전(기선)대비명현개선，차이유통계학의의；B조차이무통계학의의；A조여B조비교，차이유통계학의의。결론금궤신기환치료아주병단기료효량호，단장기료효잉유대관찰연구。
Objective Clinical curative effect evaluation of Jinkui Shenqi Pill in the treatment of periodontal disease. Methods 120 patients with periodontal disease, the Chinese medicine dialectical diagnosis of Shenqi losses; 120 patients were randomly divided into two groups, A group of 60 cases treated by TCM, a full supragingival, subgingival ultrasonic scaling, removal of plaque, first in Jinkui Shenqi Pill decoction, daily 1 agent, 2 times/day, 2 weeks after taking decoction, pill Guifu Dihuang Pill, 8 pills each time, 2 times/d, 2 weeks as a course of treatment, the curative effect after the 3 course of treatment. Group B received a full supragingival, subgingival ultrasonic scaling. Curative effect were measured before treatment(baseline), after treatment for 4 weeks, 12 weeks were examined by recording each of PLI, SBI, PD, AL, and BOP clinical indicators of periodontal detection. Results In group A after treatment for 4 weeks, 12 weeks of PLI, SBI, PD, AL, BOP were measured before and after treatment efficacy(baseline) contrast is improved obviously, the difference was statistically significant; there was no significant difference in B group; A group compared with B group, the difference has not very significant. Conclusion Jinkui Shenqi Pill in the treatment of periodontal disease to get short-term clinical curative effect good, but the long-term efficacy remains to be seen on.