CAJ | 학술논문

目的研究围绝经期妇女雌激素水平和心血管疾病的相关性。方法选择2009年6月～2012年6月我院门诊收治的83例围绝经期妇女为观察组，另选取同时期于我院门诊就诊的83例绝经前期妇女为对照组。检测两组妇女体内三酰甘油（TG）、总胆固醇（TC）、高密度脂蛋白（HDL-C）、低密度脂蛋白（LDL-C）的水平；检测围绝经期妇女血清中雌二醇（E2）水平。结果围绝经期妇女与绝经前期女性比较，具有更高的心率与血压、心血管疾病发病率，存在着一定程度的血脂异常，差异有统计学意义（P＜0.05）；围绝经期妇女雌激素水平与心血管疾病之间存在线性相关（P＜0.05）。结论围绝经期妇女雌激素水平与心血管疾病存在紧密相关。
목적연구위절경기부녀자격소수평화심혈관질병적상관성。방법선택2009년6월～2012년6월아원문진수치적83례위절경기부녀위관찰조，령선취동시기우아원문진취진적83례절경전기부녀위대조조。검측량조부녀체내삼선감유（TG）、총담고순（TC）、고밀도지단백（HDL-C）、저밀도지단백（LDL-C）적수평；검측위절경기부녀혈청중자이순（E2）수평。결과위절경기부녀여절경전기녀성비교，구유경고적심솔여혈압、심혈관질병발병솔，존재착일정정도적혈지이상，차이유통계학의의（P＜0.05）；위절경기부녀자격소수평여심혈관질병지간존재선성상관（P＜0.05）。결론위절경기부녀자격소수평여심혈관질병존재긴밀상관。
Objective To study the correlation between the estrogen levels of the perimenopausal woman and the cardiovascular disease. Methods 83 perimenopausal women treated in the outpatient department of our hospital from June 2009 to June 2012 were selected as the observation group and 83 premenopausal women treated in the outpatient department of our hospital in the corresponding period were selected as the control group.The in vivo triacylglycerol (TG),total cholesterol (TC),high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C) levels of the two groups were detected.The serum estradiol(E2)level of perimenopausal women was detected. Results Compared with premenopausal women,perimenopausal women had higher heart rate, blood pressure and incidence of cardiovascular diseases and had certain degree of dyslipidemia,with statistically significant differences(P<0.05).The estrogen levels of perimenopausal women had a linear correlation with the cardiovascular diseases (P < 0.05). Conclusion The estrogen levels of perimenopausal women have a close relationship with the cardiovascular diseases.