中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
10期
1493-1494
,共2页
2型糖尿病%混合人胰岛素%阿卡波糖
2型糖尿病%混閤人胰島素%阿卡波糖
2형당뇨병%혼합인이도소%아잡파당
Type 2 diabetes mellitus%Human insulin isophane%Acarbose
目的 探讨精蛋白生物合成人胰岛素注射液(预混30R)联合阿卡波糖治疗2型糖尿病(T2DM)的临床疗效.方法 选择189例T2DM患者,按数字表法将患者随机分为联合用药组和对照组,两组患者给予相同的基础治疗,联合用药组给予预混30R与阿卡波糖治疗,对照组给予预混30R治疗,比较两组临床疗效.结果 经过3个月的治疗,两组患者治疗后空腹血糖(FBG)及餐后2h血糖(PBG)均有不同程度改善(t =1.987、2.632、2.009、2.687,均P＜0.05),联合用药组餐后PBG[(7.3±2.7) mmol/L]及有效率(97.9％)均优于对照组[(8.7±4.1) mmol/L、89.4％](t=2.687,x2=13.25,均P＜0.05).结论 精蛋白生物合成人胰岛素联合阿卡波糖治疗T2DM,疗效稳定可靠.
目的 探討精蛋白生物閤成人胰島素註射液(預混30R)聯閤阿卡波糖治療2型糖尿病(T2DM)的臨床療效.方法 選擇189例T2DM患者,按數字錶法將患者隨機分為聯閤用藥組和對照組,兩組患者給予相同的基礎治療,聯閤用藥組給予預混30R與阿卡波糖治療,對照組給予預混30R治療,比較兩組臨床療效.結果 經過3箇月的治療,兩組患者治療後空腹血糖(FBG)及餐後2h血糖(PBG)均有不同程度改善(t =1.987、2.632、2.009、2.687,均P＜0.05),聯閤用藥組餐後PBG[(7.3±2.7) mmol/L]及有效率(97.9％)均優于對照組[(8.7±4.1) mmol/L、89.4％](t=2.687,x2=13.25,均P＜0.05).結論 精蛋白生物閤成人胰島素聯閤阿卡波糖治療T2DM,療效穩定可靠.
목적 탐토정단백생물합성인이도소주사액(예혼30R)연합아잡파당치료2형당뇨병(T2DM)적림상료효.방법 선택189례T2DM환자,안수자표법장환자수궤분위연합용약조화대조조,량조환자급여상동적기출치료,연합용약조급여예혼30R여아잡파당치료,대조조급여예혼30R치료,비교량조림상료효.결과 경과3개월적치료,량조환자치료후공복혈당(FBG)급찬후2h혈당(PBG)균유불동정도개선(t =1.987、2.632、2.009、2.687,균P＜0.05),연합용약조찬후PBG[(7.3±2.7) mmol/L]급유효솔(97.9％)균우우대조조[(8.7±4.1) mmol/L、89.4％](t=2.687,x2=13.25,균P＜0.05).결론 정단백생물합성인이도소연합아잡파당치료T2DM,료효은정가고.
Objective To explore the clinical effect of insulin glargine combined with acarbose in treatment of type 2 diabetes mellitus(T2DM).Methods 189 T2DM patients were randomly divided into combined treatment group and the control group by digital table.Two groups were given the same basic treatment,combined treatment group was given glargine insulin(30R) and acarbose treatment,control group was given insulin glargine(30R) treatment.Clinical efficacy was compared between the two groups.Results After 3 months of treatment,two groups of patients after treatment,FPG and 2h glucose were improved (t =1.987,2.632,2.009,2.687,all P ＜ 0.05).In combined treatment group,2b glucose after the meal [(7.3 ± 2.7)mmol/L] and effective rate(97.9％) were better than the control group[(8.7 ± 4.1) mmol/L,89.4％] (t =2.687,x2 =13.25,all P ＜ 0.05).Conclusion Insulin glargine combined with acarbose in the treatment of T2DM had stable and reliable therapeutic effect.
