中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
24期
26-27
,共2页
同期化疗%放疗%鼻咽癌%疗效
同期化療%放療%鼻嚥癌%療效
동기화료%방료%비인암%료효
Compared with chemotherapy%Radiation therapy%Nasopharyngeal carcinoma%Curative effect
目的对同期化疗加放疗对中晚期鼻咽癌的远期疗效进行分析探讨。方法选取80例中晚期鼻咽癌患者,随机分为两组。观察组40例患者,采用同期化疗加放疗的治疗方法;对照组40例患者,采用单纯放疗的治疗方法。通过比较两组患者的局控率、生存率及转移等情况,进而对同期化疗加放疗对中晚期鼻咽癌的远期疗效进行分析探讨。结果两组患者经过治疗后,观察组总有效率95%;对照组总有效率92.5%。两组患者在临床总有效率上无显著性差异(P>0.05)。两组患者在治疗后1年、3年、5年生存率、局控率及无瘤生存率上,观察组优于对照组,两种治疗方法有显著性差异(P>0.05)。观察组治疗的肿瘤的远处转移率低于对照组,两种治疗方法有显著性差异(P<0.05)。且两组患者的不良反应处理后均得到缓解。结论同期化疗加放疗对中晚期鼻咽癌患者在长期生存率及控制肿瘤远处转移上有较好的临床效果,有一定的临床应用价值。
目的對同期化療加放療對中晚期鼻嚥癌的遠期療效進行分析探討。方法選取80例中晚期鼻嚥癌患者,隨機分為兩組。觀察組40例患者,採用同期化療加放療的治療方法;對照組40例患者,採用單純放療的治療方法。通過比較兩組患者的跼控率、生存率及轉移等情況,進而對同期化療加放療對中晚期鼻嚥癌的遠期療效進行分析探討。結果兩組患者經過治療後,觀察組總有效率95%;對照組總有效率92.5%。兩組患者在臨床總有效率上無顯著性差異(P>0.05)。兩組患者在治療後1年、3年、5年生存率、跼控率及無瘤生存率上,觀察組優于對照組,兩種治療方法有顯著性差異(P>0.05)。觀察組治療的腫瘤的遠處轉移率低于對照組,兩種治療方法有顯著性差異(P<0.05)。且兩組患者的不良反應處理後均得到緩解。結論同期化療加放療對中晚期鼻嚥癌患者在長期生存率及控製腫瘤遠處轉移上有較好的臨床效果,有一定的臨床應用價值。
목적대동기화료가방료대중만기비인암적원기료효진행분석탐토。방법선취80례중만기비인암환자,수궤분위량조。관찰조40례환자,채용동기화료가방료적치료방법;대조조40례환자,채용단순방료적치료방법。통과비교량조환자적국공솔、생존솔급전이등정황,진이대동기화료가방료대중만기비인암적원기료효진행분석탐토。결과량조환자경과치료후,관찰조총유효솔95%;대조조총유효솔92.5%。량조환자재림상총유효솔상무현저성차이(P>0.05)。량조환자재치료후1년、3년、5년생존솔、국공솔급무류생존솔상,관찰조우우대조조,량충치료방법유현저성차이(P>0.05)。관찰조치료적종류적원처전이솔저우대조조,량충치료방법유현저성차이(P<0.05)。차량조환자적불량반응처리후균득도완해。결론동기화료가방료대중만기비인암환자재장기생존솔급공제종류원처전이상유교호적림상효과,유일정적림상응용개치。
Objective To the same period the long-term efifcacy of chemotherapy plus radiotherapy for locally advanced nasopharyngeal carcinoma were analyzed. Methods Select 80 cases of middle-late stage patients with nasopharyngeal carcinoma (NPC), randomly divided into two groups. Observation group 40 patients, using chemotherapy plus radiation therapy at the same time;Control group of 40 patients, using simple radiotherapy treatment. By comparing two groups of patients with local control rate, survival rate and transfer, etc., in the same period the long-term efifcacy of chemotherapy plus radiotherapy for locally advanced nasopharyngeal carcinoma were analyzed. Results Two groups of patients after treatment, the observation group total effective rate 95%;The control group total effective rate 92.5%. Two groups of patients with no signiifcant differences in clinical total effective rate (P>0.05). Two groups of patients after treatment for 1 year, 3 years, 5 years survival rate, local control rate and disease-free survival rates, the observation group is better than that of control group, two treatment methods have signiifcant difference (P>0.05). Observation group treated tumor distant metastasis rate is lower than the control group, two treatment methods have signiifcant difference (P<0.05). And the adverse reaction of two groups of patients were alleviated after processing. Conclusion Compared with chemotherapy plus radiotherapy for locally advanced nasopharyngeal carcinoma patients on long-term survival and control tumor distant metastasis has good clinical effect, has certain clinical application value.