CAJ | 학술논문

目的：探讨重症监护病房（IC U ）病原菌分布及其耐药情况。方法收集从 IC U送检标本中分离的病原菌668株。采用 VIT EK 2 Compact全自动微生物鉴定及药敏分析仪进行微生物敏感性试验，头孢哌酮/舒巴坦的微生物敏感性检测采用纸片扩散抗菌试验（K-B ）。结果668株病原菌来自患者痰液[434（65．0％）]、血液[83（12．0％）]、尿液[88（13．0％）]、引流液[14（2．0％）]、分泌物14（2．0％）]及其他[35（5．2％）]。革兰阴性菌以鲍氏不动杆菌检出最多，除左氧氟沙星、复方磺胺甲基异噁唑和阿米卡星外，鲍氏不动杆菌对其他药物的耐药率超过50％；革兰阳性菌以金黄色葡萄球菌居多，葡萄球菌对呋喃妥因、奎奴普丁/达福普汀、替加环素和万古霉素的敏感性好。真菌以白色念珠菌分离率最高。结论 IC U病原菌耐药情况严重，应加强病原菌种类及其耐药情况监测。
목적：탐토중증감호병방（IC U ）병원균분포급기내약정황。방법수집종 IC U송검표본중분리적병원균668주。채용 VIT EK 2 Compact전자동미생물감정급약민분석의진행미생물민감성시험，두포고동/서파탄적미생물민감성검측채용지편확산항균시험（K-B ）。결과668주병원균래자환자담액[434（65．0％）]、혈액[83（12．0％）]、뇨액[88（13．0％）]、인류액[14（2．0％）]、분비물14（2．0％）]급기타[35（5．2％）]。혁란음성균이포씨불동간균검출최다，제좌양불사성、복방광알갑기이오서화아미잡성외，포씨불동간균대기타약물적내약솔초과50％；혁란양성균이금황색포도구균거다，포도구균대부남타인、규노보정/체복보정、체가배소화만고매소적민감성호。진균이백색념주균분리솔최고。결론 IC U병원균내약정황엄중，응가강병원균충류급기내약정황감측。
Objective To investigate the distribution of pathogens in intensive care units (ICU ) and their drug resistance . Methods 668 strains of pathogens isolated from specimens from ICU were collected .VITEK 2 Compact automated microbial iden-tification and susceptibility analyzer was utilized to conduct the antimicrobial susceptibility tests .Kirby-Bauer disk diffusion suscep-tibility test(K-B) was employed to conduct the antimicrobial susceptibility test for Gram-negative bacteria cefoperazone/sulbactam . Results 668 strains of pathogens were derived from sputum [434 (65 .0% )] ,blood[83(12 .0% )] ,urine[88(13 .0% )] ,drainage [14(2 .0% )] ,secretions[14(2 .0% )] and other[35(5 .2% )] .Acinetobacter baumannii was the major detected pathogen in Gram-negative bacteria and the resistance rates were over 50% toward other drug excepting levofloxacin ,sulfamethoxazole and amikacin . Staphylococcus Staphylococcus was the major detected pathogen in Gram-positive bacteria and it showed good sensitivity toward ni-trofurantoin ,quinupristin/dalfopristin ,tigecycline and vancomycin .Candida albicans demonstrated the highest detection rate in fun-gi .Conclusion ICU pathogens have drug resistance in serious condition ,and pathogens and drug resistance monitoring should be strengthened .