医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2013年
26期
155-156
,共2页
吡拉西坦注射液%颅脑损伤%脑水肿
吡拉西坦註射液%顱腦損傷%腦水腫
필랍서탄주사액%로뇌손상%뇌수종
Peracetam Injection%ceraniocerebral%Cerebral edema
目的：观察吡拉西坦注射液治疗创伤性脑水肿的临床效果。方法：将我院近一年收治的62例创伤性脑水肿患者62例随机分为对照组和治疗组，其中：治疗组31例，静滴20%吡拉西坦注射液治疗；对照组31例，静滴20%甘露醇治疗。通过患者的头痛、呕吐症状，意识状态的变化，视乳头水肿以及头颅C T水肿带的好转等，观察药物的疗效。通过测定两组治疗前后肾功能以及血电解质的变化，观察药物的副作用。结果：治疗组显效4例，有效24例，无效2例；对照组显效5例，有效22例，无效3例.两组的总有效率分别为93.33%和90.00%，无显著性差异(P>0.05)。在用药期间和用药后治疗组没有观察到与所用药品有关的副作用，对照组有一例用药5天后出现甘露醇肾病。结论：吡拉西坦注射液治疗创伤性脑水肿疗效肯定且安全，值得临床推广。
目的：觀察吡拉西坦註射液治療創傷性腦水腫的臨床效果。方法：將我院近一年收治的62例創傷性腦水腫患者62例隨機分為對照組和治療組，其中：治療組31例，靜滴20%吡拉西坦註射液治療；對照組31例，靜滴20%甘露醇治療。通過患者的頭痛、嘔吐癥狀，意識狀態的變化，視乳頭水腫以及頭顱C T水腫帶的好轉等，觀察藥物的療效。通過測定兩組治療前後腎功能以及血電解質的變化，觀察藥物的副作用。結果：治療組顯效4例，有效24例，無效2例；對照組顯效5例，有效22例，無效3例.兩組的總有效率分彆為93.33%和90.00%，無顯著性差異(P>0.05)。在用藥期間和用藥後治療組沒有觀察到與所用藥品有關的副作用，對照組有一例用藥5天後齣現甘露醇腎病。結論：吡拉西坦註射液治療創傷性腦水腫療效肯定且安全，值得臨床推廣。
목적：관찰필랍서탄주사액치료창상성뇌수종적림상효과。방법：장아원근일년수치적62례창상성뇌수종환자62례수궤분위대조조화치료조，기중：치료조31례，정적20%필랍서탄주사액치료；대조조31례，정적20%감로순치료。통과환자적두통、구토증상，의식상태적변화，시유두수종이급두로C T수종대적호전등，관찰약물적료효。통과측정량조치료전후신공능이급혈전해질적변화，관찰약물적부작용。결과：치료조현효4례，유효24례，무효2례；대조조현효5례，유효22례，무효3례.량조적총유효솔분별위93.33%화90.00%，무현저성차이(P>0.05)。재용약기간화용약후치료조몰유관찰도여소용약품유관적부작용，대조조유일례용약5천후출현감로순신병。결론：필랍서탄주사액치료창상성뇌수종료효긍정차안전，치득림상추엄。
Objective :To investigate the effect of piracetam injection on reduction the traumatic brain edema. Methods:62 patients with traumatic encephaledemal were divided into the treatment group and the control group,31 cases were injected by the 20% piracetam injection,the other 31 cases were injected by the 20% mannitol..Observing the manifestation including headach,vomit,consciousness,papil edma and encephaledema of cranial CT,Determining the change of renal function and electrolyte in blood.Results: The total effective rate of two group was 93.33% and 90.00%,no significant diffevence(P>0.05).No adverse reactions was observed in the treatment group during and after treatment.One case appeared with Mannitol renal disease in the control group after medicine for five days.Conclusion:The effect of piracetam injection on reduction the traumatic brain edema is safe and rehable,it was worthy of clinical promotion.
