中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
38期
6846-6852
,共7页
生物材料%生物材料临床实践%生物活性玻璃离子%牙本质敏感症%龈下刮治%根面平整%目测类比疼痛评分
生物材料%生物材料臨床實踐%生物活性玻璃離子%牙本質敏感癥%齦下颳治%根麵平整%目測類比疼痛評分
생물재료%생물재료림상실천%생물활성파리리자%아본질민감증%간하괄치%근면평정%목측류비동통평분
背景：NovaMin是一种生物活性玻璃离子，其有效成分与唾液发生反应后形成羟基磷灰石晶体沉积在牙齿表面，封闭暴露的牙本质小管，可用于治疗牙本质过敏症。<br> 目的：观察龈下刮治和根面平整后含NovaMin生物活性玻璃子牙膏对患牙敏感症的影响。<br> 方法：从543例患者中按照纳入和排除标准筛选出96例慢性牙周炎患者参加试验，遵照随机、双盲、对照的原则随机分成2组，进行龈下刮治和根面平整后，试验组用含NovaMin生物活性材料的专效修复抗敏牙膏刷牙，对照组用不含NovaMin生物活性材料的牙膏刷牙。分别在抗敏试验前和抗敏试验后4周采用目测类比疼痛评分评价患牙空气刺激的敏感程度。<br> 结果与结论：共88例患者完成试验，两组各44例。使用牙膏4周后，试验组目测类比疼痛评分由抗敏试验前时的4.25±1.87降低至2.53±1.22，试验前后比较差异有显著性意义(P <0.05)；对照组目测类比疼痛评分由抗敏试验前时的4.03±1.92降低至3.63±1.45，试验前后比较差异有显著性意义(P <0.05)；试验组降低程度较对照组更明显(P <0.05)。表明含NovaMin生物活性玻璃离子的抗敏感牙膏可有效减缓龈下刮治和根面平整术后的牙本质过敏症状。
揹景：NovaMin是一種生物活性玻璃離子，其有效成分與唾液髮生反應後形成羥基燐灰石晶體沉積在牙齒錶麵，封閉暴露的牙本質小管，可用于治療牙本質過敏癥。<br> 目的：觀察齦下颳治和根麵平整後含NovaMin生物活性玻璃子牙膏對患牙敏感癥的影響。<br> 方法：從543例患者中按照納入和排除標準篩選齣96例慢性牙週炎患者參加試驗，遵照隨機、雙盲、對照的原則隨機分成2組，進行齦下颳治和根麵平整後，試驗組用含NovaMin生物活性材料的專效脩複抗敏牙膏刷牙，對照組用不含NovaMin生物活性材料的牙膏刷牙。分彆在抗敏試驗前和抗敏試驗後4週採用目測類比疼痛評分評價患牙空氣刺激的敏感程度。<br> 結果與結論：共88例患者完成試驗，兩組各44例。使用牙膏4週後，試驗組目測類比疼痛評分由抗敏試驗前時的4.25±1.87降低至2.53±1.22，試驗前後比較差異有顯著性意義(P <0.05)；對照組目測類比疼痛評分由抗敏試驗前時的4.03±1.92降低至3.63±1.45，試驗前後比較差異有顯著性意義(P <0.05)；試驗組降低程度較對照組更明顯(P <0.05)。錶明含NovaMin生物活性玻璃離子的抗敏感牙膏可有效減緩齦下颳治和根麵平整術後的牙本質過敏癥狀。
배경：NovaMin시일충생물활성파리리자，기유효성분여타액발생반응후형성간기린회석정체침적재아치표면，봉폐폭로적아본질소관，가용우치료아본질과민증。<br> 목적：관찰간하괄치화근면평정후함NovaMin생물활성파리자아고대환아민감증적영향。<br> 방법：종543례환자중안조납입화배제표준사선출96례만성아주염환자삼가시험，준조수궤、쌍맹、대조적원칙수궤분성2조，진행간하괄치화근면평정후，시험조용함NovaMin생물활성재료적전효수복항민아고쇄아，대조조용불함NovaMin생물활성재료적아고쇄아。분별재항민시험전화항민시험후4주채용목측류비동통평분평개환아공기자격적민감정도。<br> 결과여결론：공88례환자완성시험，량조각44례。사용아고4주후，시험조목측류비동통평분유항민시험전시적4.25±1.87강저지2.53±1.22，시험전후비교차이유현저성의의(P <0.05)；대조조목측류비동통평분유항민시험전시적4.03±1.92강저지3.63±1.45，시험전후비교차이유현저성의의(P <0.05)；시험조강저정도교대조조경명현(P <0.05)。표명함NovaMin생물활성파리리자적항민감아고가유효감완간하괄치화근면평정술후적아본질과민증상。
BACKGROUND:NovaMin is a kind of bioactive glass, and its active ingredients react with saliva to form hydroxyapatite crystals, which deposit on the surface of the teeth and can close the exposed dentinal tubules. It can be used for the treatment of dentin hypersensitivity. <br> OBJECTIVE:To study the effect of toothpaste containing NovaMin on tooth hypersensitivity patients after subgingival scaling and root planing surgery. <br> METHODS:According to inclusion and exclusion criteria, 96 patients were picked out from 543 patients to participate in the experiment. In compliance with the principle of randomized, double-blind, comparison, 98 subjects were randomly divided into two groups:experiment group in which the toothpaste containing NovaMin was used, and control group in which the toothpaste without NovaMin was used. Visual analog scale scoring was used to evaluate the degree of sensitivity to air stimulus respectively before and 4 weeks after al ergy experiment. <br> RESULTS AND CONCLUSION:Total y 88 patients completed the experiment. After treatment with toothpaste for 4 weeks, visual analog scale scores in the experiment group decreased from 4.25±1.87 at baseline to 2.53±1.22 by air stimulus, and visual analog scale scores in the control group decreased from 4.03±1.92 at baseline to 3.63±1.45. The visual analog scale scores in the experiment group and control group both reduced, and the difference was with statistics significance (P<0.05). Compared with the control group, visual analog scale scores in the experiment group decreased more significantly. It showed that the toothpaste containing NovaMin has significant effect on dentin hypersensitivity after subgingival scaling and root planing surgery.
