CAJ | 학술논문

背景：多项体外实验证实硅酸三钙不仅可以通过自固化过程与牙本质紧密结合，而且在生理环境下能诱导牙本质再矿化，有效阻塞牙本质小管。 　　目的：进一步验证硅酸三钙对牙本质小管的封闭作用。 　　方法：选择正畸患者拔除的第一前磨牙制作离体牙本质盘36块，分别经0.29 mol/L EDTA 内浸置2 min，6%柠檬酸蚀1 min 后冲洗，蒸馏水超声清洗20 min 3种方法预处理，模拟具有牙本质小管不同开放程度的牙本质敏感症。以上每组随机分为3个亚组，即硅酸三钙组、氟化钠对照组、空白对照组，前2组每天早晚分别用对应材料涂刷表面，2 min/次，空白对照组不处理，其余时间全部置于人工唾液37℃恒温箱中保存。14 d后通过扫描电镜观察各组处理前后牙本质形态，并计算开放牙本质小管直径和面积。 　　结果与结论：经不同预处理后牙本质小管都呈开放状态，但柠檬酸和EDTA预处理溶液较蒸馏水有更强的脱矿作用，牙本质小管更加清晰。各组经氟化钠或硅酸三钙涂擦后，牙本质小管口有不同程度沉积物，且开放牙本质小管面积及平均直径较空白对照组小(P<0.05)；经硅酸三钙涂擦的牙本质小管几乎完全均质封闭，偶见有单个孤立开放的牙本质小管口，开放牙本质小管面积及平均直径都明显低于氟化钠对照组(P<0.05)。证实硅酸三钙可有效封闭牙本质小管，且效果优于氟化钠；在治疗牙本质过敏时，如果先用EDTA或酸蚀剂处理，脱敏效果会更完善。
배경：다항체외실험증실규산삼개불부가이통과자고화과정여아본질긴밀결합，이차재생리배경하능유도아본질재광화，유효조새아본질소관。 　　목적：진일보험증규산삼개대아본질소관적봉폐작용。 　　방법：선택정기환자발제적제일전마아제작리체아본질반36괴，분별경0.29 mol/L EDTA 내침치2 min，6%저몽산식1 min 후충세，증류수초성청세20 min 3충방법예처리，모의구유아본질소관불동개방정도적아본질민감증。이상매조수궤분위3개아조，즉규산삼개조、불화납대조조、공백대조조，전2조매천조만분별용대응재료도쇄표면，2 min/차，공백대조조불처리，기여시간전부치우인공타액37℃항온상중보존。14 d후통과소묘전경관찰각조처리전후아본질형태，병계산개방아본질소관직경화면적。 　　결과여결론：경불동예처리후아본질소관도정개방상태，단저몽산화EDTA예처리용액교증류수유경강적탈광작용，아본질소관경가청석。각조경불화납혹규산삼개도찰후，아본질소관구유불동정도침적물，차개방아본질소관면적급평균직경교공백대조조소(P<0.05)；경규산삼개도찰적아본질소관궤호완전균질봉폐，우견유단개고립개방적아본질소관구，개방아본질소관면적급평균직경도명현저우불화납대조조(P<0.05)。증실규산삼개가유효봉폐아본질소관，차효과우우불화납；재치료아본질과민시，여과선용EDTA혹산식제처리，탈민효과회경완선。
BACKGROUND:A number of in vitro experiments have confirmed that the tricalcium silicate not only can be closely integrated with the dentin through self-curing process, but also can induce dentin remineralization in the physiological environment, thereby effectively blocking the dentinal tubules. OBJECTIVE:To further verify the effects of tricalcium silicate solution on the occlusion of dentinal tubules. METHODS:Thirty-six dentinal discs were made of free first premolars from orthodontic patients, and divided into three pretreatment groups randomly. The teeth were soaked in pretreatment solution for 2 minutes, namely 0.29 mol/L ethylene diamine tetraacetie acid, 6%citric acid, and rinsed ultrasonical y with deionized water 20 minutes, respectively. Every above-mentioned group was randomly assigned into experimental group (tricalcium silicate), control group (sodium fluoride) and blank group, and corresponding materials in each group were used to coat the outer dentinal tubules (2 minutes/time). Then, the dentinal discs were saved in artificial saliva in a 37 observed using scanning electron microscope. Diameter and area of open dentinal tubules were calculated. RESULTS AND CONCLUSION:After pretreatment, the dentinal tubules were at open state;except for the blank control group to maintain the original state, acid etching and ethylene diamine tetraacetie acid pretreatment solutions had a stronger capacity of demineralization, which led to the dentinal tubules open. After the dentinal tubules were treated with sodium fluoride and tricalcium silicate, there were varying degrees of sediments, and open dentinal tubule area and average diameter in the sodium fluoride and tricalcium silicate groups were lower than those in the control group (P<0.05). The dentinal tubule treated with tricalcium silicate was almost entirely closed homogeneously, and occasional y, a single open dentinal tubule was seen. Open dentinal tubule area and average diameter in the tricalcium silicate group were significantly lower than those in the sodium fluoride group (P<0.05). The findings verify that dentin occlusion using tricalcium silicate is superior to that using sodium fluoride;and dentin tubule pretreatment with acid etching or ethylene diamine tetraacetie acid is beneficial to desensitization effects.