CAJ | 학술논문

目的：研究急性百草枯中毒患者的百草枯含量、肾功能指标和肺功能指标与其预后关系。方法：选择107例急性百草枯中毒患者为研究对象，根据预后分为存活组和死亡组，检测患者血尿的百草枯含量、肾功能指标和肺功能指标。结果：死亡组患者的血浆百草枯含量、尿液百草枯含量分别为9．54±1．13 mg/和423．23±63．43 mg/L均高于存活组；血肌酐、血尿素氮、二氧化碳分压（PaCO2）分别为141．8±18．2mmol/L、11．4±2．2mmol/L和1．32±6．32mmHg，均高于存活组，氧分压（PaO2）、实际碳酸氢盐（PCO3-）和剩余碱（BE）分别为79．44±10．42mmHg、14．82±2．45mmol/L和（-14．56±3．42） mmol/L，均低于存活组（P＜0．05）。结论：百草枯中毒患者的百草枯含量、肺功能和肾功能指标与其预后密切相关，百草枯含量、血肌酐、血尿素氮、PaCO2、剩余碱可提示患者的存活情况。
목적：연구급성백초고중독환자적백초고함량、신공능지표화폐공능지표여기예후관계。방법：선택107례급성백초고중독환자위연구대상，근거예후분위존활조화사망조，검측환자혈뇨적백초고함량、신공능지표화폐공능지표。결과：사망조환자적혈장백초고함량、뇨액백초고함량분별위9．54±1．13 mg/화423．23±63．43 mg/L균고우존활조；혈기항、혈뇨소담、이양화탄분압（PaCO2）분별위141．8±18．2mmol/L、11．4±2．2mmol/L화1．32±6．32mmHg，균고우존활조，양분압（PaO2）、실제탄산경염（PCO3-）화잉여감（BE）분별위79．44±10．42mmHg、14．82±2．45mmol/L화（-14．56±3．42） mmol/L，균저우존활조（P＜0．05）。결론：백초고중독환자적백초고함량、폐공능화신공능지표여기예후밀절상관，백초고함량、혈기항、혈뇨소담、PaCO2、잉여감가제시환자적존활정황。
Objective:To study the relation between paraquat levels , renal function and lung function in patients with acute paraquat poi-soning and its prognosis .Methods:107 patients with acute paraquat poisoning were studied , were divided into survival group and death group according to the prognosis , paraquat levels , renal function and lung function was detected in the patients .Results:Plasma levels, urine paraquat levels was (9.54 ±1.13,423.23 ±63.43) mg/L in the death group, was higher than that in the survival group .Serum creatinine, blood urea nitrogen, carbon dioxide partial pressure (PaCO2) was (141.8 ±18.2)mmol/L,(11.4 ±2.2)mmol/L and(41.32 ±6.32)mmHg,higher than that in the survival group , pressure of oxygen (PaO2),actual bicarbonate (PCO3-) and base excess (BE) was(79.44 ±10.42)mmHg,(14.82 ±2.45)mmol/L and(-14.56 ±3.42) mmol/L,lower than that in the survival group (P<0.05). Conclusion:The content of paraquat , pulmonary and renal function in the patients with paraquat poisoning have a close relation with its prognosis, paraquat levels, serum creatinine ,blood urea nitrogen, PaCO2 and base excess may prompt the patient's survival.