CAJ | 학술논문

目的：探讨放射性核素肾动态显像GFR（肾小球滤过率）评价肾功能与血清肌酐（ Scre）清除率评价肾功能的比较。方法：首先对照组估算我科GFR的正常参考值；80例当肾功能受损害时，GFR的测量值与血清肌酐清除率测定值的比较。结果：80例患者的GFR与肌酐清除率对比，GFR和血清肌酐均异常者63例，其GFR值81．3±12．8ml/min与肌酐清除率85．5±11．3ml/min，差异无显著性意义（P＞0．05）；12例慢性肾损害患者，肌酐清除率70．1±8．3ml/min，GFR值50．2±6．8ml/min，差异有显著性意义（P＜0．01）；5例重度肾积水患者GFR值19．1±7．3ml/min，肌酐清除率23．6±5．8ml/min，差异有显著性意义（P＜0．01）。放射性核素肾动态GFR值与肌酐清除率的数值较符合；且在肾功能受损早期GFR比肌酐清除率表现更早异常改变。结论：放射性核素肾动态检查GFR测定更能早期反映肾小球率过滤功能改变，能较准确的估算分肾功能。
목적：탐토방사성핵소신동태현상GFR（신소구려과솔）평개신공능여혈청기항（ Scre）청제솔평개신공능적비교。방법：수선대조조고산아과GFR적정상삼고치；80례당신공능수손해시，GFR적측량치여혈청기항청제솔측정치적비교。결과：80례환자적GFR여기항청제솔대비，GFR화혈청기항균이상자63례，기GFR치81．3±12．8ml/min여기항청제솔85．5±11．3ml/min，차이무현저성의의（P＞0．05）；12례만성신손해환자，기항청제솔70．1±8．3ml/min，GFR치50．2±6．8ml/min，차이유현저성의의（P＜0．01）；5례중도신적수환자GFR치19．1±7．3ml/min，기항청제솔23．6±5．8ml/min，차이유현저성의의（P＜0．01）。방사성핵소신동태GFR치여기항청제솔적수치교부합；차재신공능수손조기GFR비기항청제솔표현경조이상개변。결론：방사성핵소신동태검사GFR측정경능조기반영신소구솔과려공능개변，능교준학적고산분신공능。
Objective:To study radionuclide renal dynamic imaging GFR ( glomerular filtration rate ) to evaluate renal function and se-rum creatinine ( Scre) evaluation comparison of renal clearance .Methods:First estimation of normal reference value of my GFR in the control group;when renal function damage of 80 cases, measurement of GFR and creatinine clearance rate comparison of measurement val-ues.Results:80 cases patients of GFR and muscle anhydride cleared rate contrast , GFR and serum muscle anhydride are exception who 63 cases, its GFR value 81.3 ±12.8ml/min and muscle anhydride cleared rate 85.5 ±11.3ml/min, differences no significantly sexual meaning (P>0.05);12 cases chronic kidney damage patients , muscle anhydride cleared rate 70.1 ±8.3ml/min,GFR value 50.2 ± 6.8ml/min, differences has significantly sexual meaning ( P<0.01); Value of 5 patients with severe hydronephrosis GFR 19.1 ±7. 3ml/min, 23.6 ±5.8ml/min creatinine clearance rate, the difference has a significant meaning (P<0.01).Radionuclide renal dynam-ic values of GFR and creatinine clearance rate more in line with;early GFR and impaired renal function creatinine clearance rate of earlier abnormal changes .Conclusion:Radionuclide renal dynamic checking GFR determination can better reflect the change rate of Glomerular filtration function in early stage , a more accurate estimation of renal function .