中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
15期
2455-2460
,共6页
邓桢翰%杨拓%李辉%张屹%李宇晟%雷光华
鄧楨翰%楊拓%李輝%張屹%李宇晟%雷光華
산정한%양탁%리휘%장흘%리우성%뢰광화
组织构建%骨组织工程%疼痛%泥疗法%膝关节%骨关节炎%荟萃分析
組織構建%骨組織工程%疼痛%泥療法%膝關節%骨關節炎%薈萃分析
조직구건%골조직공정%동통%니요법%슬관절%골관절염%회췌분석
osteoarthritis,knee%pain%mud therapy%evidence-based medicine
背景:泥浴疗法治疗膝骨关节炎一直受到研究者的重视,但其有效性在以往的各项研究中尚存在争议。
<br> 目的:分析研究泥浴疗法治疗膝骨关节炎疼痛的有效性。
<br> 方法:计算机检索 Pubmed/Medline 数据库以及手工检索相关文献的参考文献。所有检索截止至2013年3月9日。收集国内外公开发表的有关泥浴疗法治疗膝骨关节炎的随机对照试验和前瞻性对照试验。
<br> 结果与结论:纳入Meta分析的研究共7个,累计研究对象410例。治疗组和对照组的目测类比疼痛评分(标准化标准差[SMD]-0.74)和 WOMAC 疼痛评分(标准化标准差[SMD]-0.30)组间差异有显著性意义。可见泥浴疗法可改善膝骨关节炎疼痛的症状。但此结论有待更多高质量的随机对照试验进一步证实。
揹景:泥浴療法治療膝骨關節炎一直受到研究者的重視,但其有效性在以往的各項研究中尚存在爭議。
<br> 目的:分析研究泥浴療法治療膝骨關節炎疼痛的有效性。
<br> 方法:計算機檢索 Pubmed/Medline 數據庫以及手工檢索相關文獻的參攷文獻。所有檢索截止至2013年3月9日。收集國內外公開髮錶的有關泥浴療法治療膝骨關節炎的隨機對照試驗和前瞻性對照試驗。
<br> 結果與結論:納入Meta分析的研究共7箇,纍計研究對象410例。治療組和對照組的目測類比疼痛評分(標準化標準差[SMD]-0.74)和 WOMAC 疼痛評分(標準化標準差[SMD]-0.30)組間差異有顯著性意義。可見泥浴療法可改善膝骨關節炎疼痛的癥狀。但此結論有待更多高質量的隨機對照試驗進一步證實。
배경:니욕요법치료슬골관절염일직수도연구자적중시,단기유효성재이왕적각항연구중상존재쟁의。
<br> 목적:분석연구니욕요법치료슬골관절염동통적유효성。
<br> 방법:계산궤검색 Pubmed/Medline 수거고이급수공검색상관문헌적삼고문헌。소유검색절지지2013년3월9일。수집국내외공개발표적유관니욕요법치료슬골관절염적수궤대조시험화전첨성대조시험。
<br> 결과여결론:납입Meta분석적연구공7개,루계연구대상410례。치료조화대조조적목측류비동통평분(표준화표준차[SMD]-0.74)화 WOMAC 동통평분(표준화표준차[SMD]-0.30)조간차이유현저성의의。가견니욕요법가개선슬골관절염동통적증상。단차결론유대경다고질량적수궤대조시험진일보증실。
BACKGROUND:As a therapy means of osteoarthritis, mud therapy has attracted great attention from the researchers, but its effectiveness stil remains controversial in the previous studies.
<br> OBJECTIVE:To analyze the effectiveness of mud therapy for relieving knee osteoarthritis pain.
<br> METHODS:An online search through Pubmed/Medline database was performed, and the relevant literatures were manual y retrieved. The retrieval deadline was set on March 9, 2013. Randomized control ed trials and prospective control ed trials addressing mud therapy of knee osteoarthritis were col ected.
<br> RESULTS AND CONCLUSION:A total of seven studies of meta-analysis involving 410 cases were included. There was a significant difference between treatment group and control group in the visual analogue scale pain score (standardized mean difference:-0.74) and WOMAC pain score (standardized standard deviation:-0.30). Mud therapy can attenuate knee osteoarthritis pain. But this conclusion needs to be confirmed by more high-quality randomized control ed trials.