CAJ | 학술논문

目的：糖尿病神经病变是糖尿病最主要的并发症之一，本研究探讨与糖尿病周围神经病变有关的危险因素，以指导临床早期发现糖尿病足高危人群。方法：选择2011年10月到2013年2月来我院临床诊断2型糖尿病周围神经病变的患者60例，作为观察组；对照组为同期收治的2型糖尿病无周围神经病变患者60例。采用自填式问卷调查患者的一般情况，临床及实验室检查各项指标。应用 Logistic 回归分析筛选糖尿病周围神经病变的危险因素。结果：观察组与对照组在年龄，糖尿病史，文化水平，经济条件，足部感染，足部溃疡，空腹血糖以及糖化血红蛋白含量之间的差异具有统计学意义（P 均<0.05）。Logistic 回归分析显示糖尿病周围神经病变与年龄，文化水平，足部感染，空腹血糖及糖化血红蛋白之间有相关性。结论：2型糖尿病患者发生周围神经病变与多种因素有明显的相关性，经常进行相关危险因素的筛查，能有效预防和缓解神经病变的发生和进展。
목적：당뇨병신경병변시당뇨병최주요적병발증지일，본연구탐토여당뇨병주위신경병변유관적위험인소，이지도림상조기발현당뇨병족고위인군。방법：선택2011년10월도2013년2월래아원림상진단2형당뇨병주위신경병변적환자60례，작위관찰조；대조조위동기수치적2형당뇨병무주위신경병변환자60례。채용자전식문권조사환자적일반정황，림상급실험실검사각항지표。응용 Logistic 회귀분석사선당뇨병주위신경병변적위험인소。결과：관찰조여대조조재년령，당뇨병사，문화수평，경제조건，족부감염，족부궤양，공복혈당이급당화혈홍단백함량지간적차이구유통계학의의（P 균<0.05）。Logistic 회귀분석현시당뇨병주위신경병변여년령，문화수평，족부감염，공복혈당급당화혈홍단백지간유상관성。결론：2형당뇨병환자발생주위신경병변여다충인소유명현적상관성，경상진행상관위험인소적사사，능유효예방화완해신경병변적발생화진전。
Object: Diabetic neuropathy is one of the most common complications of diabetes mel itus. The aim of this study is to assess the associated risk factors among diabetic patient, in order to guide early diabetic foot diagnosis. Methods: We selected 60 patients with type 2 diabetes mel itus(T2DM) with peripheral neuropathy as the the observed group and 60 type 2 diabetes patients mel itus(T2DM) without peripheral neuropathy as the control group,who were diagnosed in our hospital from October 2011 to February 2013. Using self-administered questionnaire to investigate the patient's general condition and checking the disease-related indicators by cinical and laboratory methods. Using logistic regression to analysis risk factors of diabetic peripheral neuropathy. Results: The differences between patients with diabetic peripheral neuropathy and patients with diabetes alone on age, history of diabetes, cultural level, the economic conditions, foot infection, foot ulcers, fasting glucose and glycosylated hemoglobin levels are statistical y significant(p<0.5). Diabetic peripheral neuropathy is associated with age, the culture level, foot infection, fasting glucose and glycosylated hemoglobin levels il ustrated by logistic regression. Conclusion: There is an obvious correlation with many factors for patients with type 2 diabetes mel itus to generate peripheral neuropathy. Regular screening for related risk factors can effectively prevent and al eviate the occurrence and progress of neuropathy.