CAJ | 학술논문

目的：了解宜州市婚检人群地中海贫血（地贫）的发生情况。方法采用血细胞分析和血红蛋白电泳对宜州市2011～2012年20830例婚检人员进行地贫筛查。结果20830例婚检者中，血细胞分析检出地贫3310例（15．89％）。血红蛋白电泳检出疑α-地贫1153例（5．54％），其中疑轻型α-地贫1008例、中间型α-地贫57例、疑β复合α地贫88例；疑β-地贫1170例（5．62％）；异常Hb 34例（0．16％）。结论宜州市婚检人群地中海贫血检出率较高，婚前筛查是预防地贫的主要手段。
목적：료해의주시혼검인군지중해빈혈（지빈）적발생정황。방법채용혈세포분석화혈홍단백전영대의주시2011～2012년20830례혼검인원진행지빈사사。결과20830례혼검자중，혈세포분석검출지빈3310례（15．89％）。혈홍단백전영검출의α-지빈1153례（5．54％），기중의경형α-지빈1008례、중간형α-지빈57례、의β복합α지빈88례；의β-지빈1170례（5．62％）；이상Hb 34례（0．16％）。결론의주시혼검인군지중해빈혈검출솔교고，혼전사사시예방지빈적주요수단。
Objective To learn the occurrence of thalassemia among people participating in premarital examination in Yizhou City.Methods The blood and hemoglobin electrophoresis analysis was applied to a screening for thalassemia in 20 830 cases participating from 2011 to 2012 in premarital examination in Yizhou City .Results Among 20 830 cases participating in premarital examination, there were 3 310 cases ( 15.89%) of thalassemia detected by blood analysis.The hemoglobin electrophoresis analysis suggested that there were 1 153(5.54%) suspected α-thalassemia cases,including 1 008 suspected mildα-thalassemia cases,57α-thalassemia intermedia cases and 88 suspected cases of co-inheritance of α-thalassemia andβ-thalassemia,1 170(5.62%) suspected β-thalassemia cases,and 34(0.16%) abnormal Hb cases.Conclusion The prevalence of thalassemia is higher among people participating in premarital examination in Yizhou City .The premarital screening is a primary means for the prevention of thalassemia .