CAJ | 학술논문

目的观察老年性白内障与糖尿病性白内障晶状体上皮细胞的超微结构,探讨晶状体上皮细胞凋亡及自噬与白内障的关系.方法用透射电镜观察5例老年性白内障及5例糖尿病性白内障晶状体上皮细胞的超微结构,并与2例透明晶状体上皮细胞的超微结构相比较.结果老年性白内障及糖尿病性白内障晶状体上皮细胞中可见细胞凋亡现象及自噬现象,而正常晶状体上皮细胞中未见凋亡及自噬现象.结论老年性白内障及糖尿病性白内障的发生、发展与晶状体上皮细胞凋亡及细胞自噬密切相关.
목적 관찰노년성백내장여당뇨병성백내장정상체상피세포적초미결구,탐토정상체상피세포조망급자서여백내장적관계.방법 용투사전경관찰5례노년성백내장급5례당뇨병성백내장정상체상피세포적초미결구,병여2례투명정상체상피세포적초미결구상비교.결과 노년성백내장급당뇨병성백내장정상체상피세포중가견세포조망현상급자서현상,이정상정상체상피세포중미견조망급자서현상.결론 노년성백내장급당뇨병성백내장적발생、발전여정상체상피세포조망급세포자서밀절상관.
Objective To study the relationship of cataract with lens epithelial cell apoptosis and autophagy by observing the ultrastructure of age-related and diabetic cataract lens epithelial cells.Methods Transmission electron microscope was used to observe the apoptotic and autophagic morphology of the lens epithelial cells in 5 cases with age-related and diabetic cataract respectively,and in 2 cases with normal lens.Results The apoptosis and autophagy of lens epithelial cells was found in cases with age-related and diabetic cataract,while no expression was observed in control lens epithelial cells.Conclusion The apoptosis and autophagy of lens epithelial cells are closely related to age-related and diabetic cataract formation.