中国实用神经疾病杂志
中國實用神經疾病雜誌
중국실용신경질병잡지
CHINESE JOURNAL OF PRACTICAL NERVOUS DISEASES
2014年
6期
25-27
,共3页
脑梗死%血清胆红素%尿酸%动脉粥样硬化
腦梗死%血清膽紅素%尿痠%動脈粥樣硬化
뇌경사%혈청담홍소%뇨산%동맥죽양경화
Cerebral infarction%Serum bilirubin%Uric acid%Atherosclerosis
目的：探讨血清胆红素（bilirubin ，BIL）及尿酸（uric acid ，UA）浓度在脑梗死（cerebral infarction ，CI）发生、发展中的作用。方法选取我院2012-02-2013-03收治的200例CI患者（观察组）及我院体检健康者180例（对照组），检测并对比2组血清总胆红素（TBIL）、直接胆红素（DBIL）、间接胆红素（IDBIL）和尿酸（UA）浓度。结果（1）观察组 TBIL、DBIL及UA浓度均明显高于对照组（P＜0.05）。（2）中重型CI组血清BIL浓度均高于轻型CI组，血清UA浓度低于轻型CI组（P＜0.05）。（3）急性CI组血清BIL浓度均明显高于亚急性CI组及对照组（P＜0.05）；亚急性CI组与对照组血清BIL浓度无显著性差异（P＞0.05）；急性和亚急性CI组UA浓度均明显高于对照组（P＜0.05），而急性与亚急性CI组之间无显著性差异（P＞0.05）。结论血清BIL升高是CI患者机体应激反应的表现，UA浓度升高可反映CI患者的动脉粥样硬化情况。
目的：探討血清膽紅素（bilirubin ，BIL）及尿痠（uric acid ，UA）濃度在腦梗死（cerebral infarction ，CI）髮生、髮展中的作用。方法選取我院2012-02-2013-03收治的200例CI患者（觀察組）及我院體檢健康者180例（對照組），檢測併對比2組血清總膽紅素（TBIL）、直接膽紅素（DBIL）、間接膽紅素（IDBIL）和尿痠（UA）濃度。結果（1）觀察組 TBIL、DBIL及UA濃度均明顯高于對照組（P＜0.05）。（2）中重型CI組血清BIL濃度均高于輕型CI組，血清UA濃度低于輕型CI組（P＜0.05）。（3）急性CI組血清BIL濃度均明顯高于亞急性CI組及對照組（P＜0.05）；亞急性CI組與對照組血清BIL濃度無顯著性差異（P＞0.05）；急性和亞急性CI組UA濃度均明顯高于對照組（P＜0.05），而急性與亞急性CI組之間無顯著性差異（P＞0.05）。結論血清BIL升高是CI患者機體應激反應的錶現，UA濃度升高可反映CI患者的動脈粥樣硬化情況。
목적：탐토혈청담홍소（bilirubin ，BIL）급뇨산（uric acid ，UA）농도재뇌경사（cerebral infarction ，CI）발생、발전중적작용。방법선취아원2012-02-2013-03수치적200례CI환자（관찰조）급아원체검건강자180례（대조조），검측병대비2조혈청총담홍소（TBIL）、직접담홍소（DBIL）、간접담홍소（IDBIL）화뇨산（UA）농도。결과（1）관찰조 TBIL、DBIL급UA농도균명현고우대조조（P＜0.05）。（2）중중형CI조혈청BIL농도균고우경형CI조，혈청UA농도저우경형CI조（P＜0.05）。（3）급성CI조혈청BIL농도균명현고우아급성CI조급대조조（P＜0.05）；아급성CI조여대조조혈청BIL농도무현저성차이（P＞0.05）；급성화아급성CI조UA농도균명현고우대조조（P＜0.05），이급성여아급성CI조지간무현저성차이（P＞0.05）。결론혈청BIL승고시CI환자궤체응격반응적표현，UA농도승고가반영CI환자적동맥죽양경화정황。
Objective To explore the effect of serum bilirubin (BIL) and uric acid (UA) levels in the occurrence and devel-opment of cerebral infarction(CI).Methods 200 patients with CI admitted in our hospital (observation group) and the 180 ca-ses of healthy subjects from physical examination (control group) from February 2012-March 2013 were selected ,serum total bilirubin (TBIL) ,direct bilirubin (DBIL) and indirect bilirubin (IDBIL) and uric acid (UA) levels of the two groups were de-tected and compared.Results (1) The TBIL ,DBIL ,UA concentrations of the observation group were significantly higher than that of control group (P<0.05). (2) The serum BIL concentration of the moderate-severe CI group were significantly higher than that of the light CI group ,serum UA concentrations were significantly lower than that of the light CI group (P<0.05).(3) The serum BIL concentration of acute CI group were significantly higher than thatof the subacute CI group and control group (P<0.05) ,while there was no significant difference between subacute CI group and the control group (P>0.05);the UA concentrations of acute and subacute CI group were significantly higher than that of control group (P<0.05) ,while there was no significant difference between acute and subacute CI group (P> 0.05).Conclusion Elevated serum BIL is the body's stress response of CI patients ,elevated and UA concentration can reflect the atherosclerosis in patients with CI.
