北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2013年
10期
38-38,39
,共2页
康肾散%慢性肾小球肾炎%24小时尿蛋白定量%气虚血瘀
康腎散%慢性腎小毬腎炎%24小時尿蛋白定量%氣虛血瘀
강신산%만성신소구신염%24소시뇨단백정량%기허혈어
Renal recovery powder%Chronic glomerulonephritis%24 hour urinary protein%Qi deficiency and blood stasis
目的：以量化评分标准为评分手段，观察康肾散治疗慢性肾小球肾炎的临床效果。方法：将60例慢性肾小球肾炎患者按照随机分组方法分为治疗组（康肾散组）30例和对照组（贝那普利组）30例。经8周治疗后观察24小时尿蛋白定量、中医症候疗效、生活质量及总疗效等指标的变化。结果：两组间总有效率有显著差异（P＜0.01），治疗组显著优于对照组；两组间降24小时尿蛋白的作用有显著差异（P＜0.05），治疗组优于对照组；两组间症候疗效及临床症候症状改善均有显著差异（P＜0.01），治疗组显著优于对照组。结论：康肾散不但能显著改善慢性肾小球肾炎患者神疲乏力、水肿、纳呆食少、腰痛、面色少华、肌肤甲错或肢体麻木等临床症状，而且能够降低24小时尿蛋白定量，并未发现不良反应。
目的：以量化評分標準為評分手段，觀察康腎散治療慢性腎小毬腎炎的臨床效果。方法：將60例慢性腎小毬腎炎患者按照隨機分組方法分為治療組（康腎散組）30例和對照組（貝那普利組）30例。經8週治療後觀察24小時尿蛋白定量、中醫癥候療效、生活質量及總療效等指標的變化。結果：兩組間總有效率有顯著差異（P＜0.01），治療組顯著優于對照組；兩組間降24小時尿蛋白的作用有顯著差異（P＜0.05），治療組優于對照組；兩組間癥候療效及臨床癥候癥狀改善均有顯著差異（P＜0.01），治療組顯著優于對照組。結論：康腎散不但能顯著改善慢性腎小毬腎炎患者神疲乏力、水腫、納呆食少、腰痛、麵色少華、肌膚甲錯或肢體痳木等臨床癥狀，而且能夠降低24小時尿蛋白定量，併未髮現不良反應。
목적：이양화평분표준위평분수단，관찰강신산치료만성신소구신염적림상효과。방법：장60례만성신소구신염환자안조수궤분조방법분위치료조（강신산조）30례화대조조（패나보리조）30례。경8주치료후관찰24소시뇨단백정량、중의증후료효、생활질량급총료효등지표적변화。결과：량조간총유효솔유현저차이（P＜0.01），치료조현저우우대조조；량조간강24소시뇨단백적작용유현저차이（P＜0.05），치료조우우대조조；량조간증후료효급림상증후증상개선균유현저차이（P＜0.01），치료조현저우우대조조。결론：강신산불단능현저개선만성신소구신염환자신피핍력、수종、납태식소、요통、면색소화、기부갑착혹지체마목등림상증상，이차능구강저24소시뇨단백정량，병미발현불량반응。
Objective:To quantify the scoring criteria for scoring method, observation of Kangshen powder in treating chronic glomerulonephritis clinical effect. Methods: 60 cases of patients with chronic glomerulonephritis according to stochastic grouping method is divided into the treatment group (kidney Kang San group) in 30 cases and the control group (Benner Pury) in 30 cases. After 8 weeks of treatment were observed in 24 hour urine protein, TCM syndrome efficacy, quality of life and the total effect index changes. Results: among two groups of the total efficiency of a very significant difference (P<0.01), the treatment group was better than control group; among the two groups in fall 24 hour urine protein function has significant difference (P<0.05), the treatment group than in control group; the clinical effect between the two groups and the clinical syndrome symptoms improved significantly differences (P<0.01), the treatment group was better than control group. Conclusion: Kangshen powder not only can significantly improve chronic glomerulonephritis patients tired, eat less respectively, China face, low back pain, edema and other clinical symptoms, but also can reduce 24 hour urinary protein, found no adverse reaction.
