CAJ | 학술논문

目的分析胃肠道间质瘤患者的病理诊断及预后。方法66例胃肠道间质瘤患者行手术后，观察和分析其病理学形态、肿瘤的大小等情况，并根据指标进行分型。结果66例胃肠道间质瘤中，CD117阳性表达60例；CD34阳性表达为45例；差异显著，具有统计学意义(P <0.05)。患者发生在小肠和胃以及结直肠、腹腔其他部位间质瘤，3年内没有复发，患者的转移生存率分别为：45.5%、83.7%、50.0%、40.0%。胃部明显优于其他部位，差异显著，具有统计学意义(P <0.05)。结论在诊断胃肠道间质瘤时可以联合应用CD34和CD117；同时根据肿瘤的大小和细胞异型性以及核分裂等组织形态学的分型来诊断胃肠道间质瘤。
목적분석위장도간질류환자적병리진단급예후。방법66례위장도간질류환자행수술후，관찰화분석기병이학형태、종류적대소등정황，병근거지표진행분형。결과66례위장도간질류중，CD117양성표체60례；CD34양성표체위45례；차이현저，구유통계학의의(P <0.05)。환자발생재소장화위이급결직장、복강기타부위간질류，3년내몰유복발，환자적전이생존솔분별위：45.5%、83.7%、50.0%、40.0%。위부명현우우기타부위，차이현저，구유통계학의의(P <0.05)。결론재진단위장도간질류시가이연합응용CD34화CD117；동시근거종류적대소화세포이형성이급핵분렬등조직형태학적분형래진단위장도간질류。
Objective analysis of gastrointestinal stromal tumors in patients with pathological diagnosis and prognosis. Methods 66 cases of gastrointestinal stromal tumor patients after surgery, observation and analysis of its pathological form, tumor size, etc., and according to indicators typing. Results 66 cases of gastrointestinal stromal tumors, CD117 expression 60 cases; CD34 expression was 45 cases; difference was significant, with statistical significance (P <0.05). Patients in the small intestine and stomach and colorectal, other parts of the abdominal cavity stromal tumors, three years without recurrence, metastasis-free survival of patients were:45.5%, 83.7%, 50.0%, 40.0%. Significantly better than other parts of the stomach and the difference was significant, with statistical significance (P <0.05). Conclusions in the diagnosis of gastrointestinal stromal tumors when combined with CD34 and CD117;simultaneously based on tumor size and mitotic cell atypia, and organizations such as the sub-type morphology to diagnose gastrointestinal stromal tumors.