世界最新医学信息文摘（电子版）
世界最新醫學信息文摘（電子版）
세계최신의학신식문적（전자판）
World Latest Medicine Information
2013年
11期
20-21
,共2页
地佐辛%无痛胃肠镜%丙泊酚
地佐辛%無痛胃腸鏡%丙泊酚
지좌신%무통위장경%병박분
Dezocine propofol%painless gastroscopy%propofol
目的观察地佐辛复合丙泊酚静脉麻醉用于无痛胃肠镜中的临床效果，探讨其安全性。方法选择100例ASAⅠ-Ⅱ级进行无痛胃肠镜检查患者随机分为两组，观察组（地佐辛复合丙泊酚静脉麻醉组）和对照组（芬太尼复合丙泊酚静脉麻醉组）各50例。记录两组患者SPO2、HR、MAP、RR变化情况及意识消失时间（睫毛反射消失时间）、术毕清醒时间、丙泊酚用量及术毕留观时间，观察两组患者镇痛反应（视觉模拟评分法VAS）、术中体动、术中呼吸抑制及术后恶心、呕吐等不良反应的发生率。结果两组患者睫毛反射消失时间、胃肠镜检查时间比较差异无统计学意义（P ＞0.05）。观察组患者的术毕清醒时间短，不良反应发生率较对照组少，术中患者生命体征更加平稳。结论地佐辛复合丙泊酚静脉麻醉用于无痛胃肠镜检查，镇痛、镇静效果满意，有较高的安全性，不良反应发生率低，值得临床推广应用。
目的觀察地佐辛複閤丙泊酚靜脈痳醉用于無痛胃腸鏡中的臨床效果，探討其安全性。方法選擇100例ASAⅠ-Ⅱ級進行無痛胃腸鏡檢查患者隨機分為兩組，觀察組（地佐辛複閤丙泊酚靜脈痳醉組）和對照組（芬太尼複閤丙泊酚靜脈痳醉組）各50例。記錄兩組患者SPO2、HR、MAP、RR變化情況及意識消失時間（睫毛反射消失時間）、術畢清醒時間、丙泊酚用量及術畢留觀時間，觀察兩組患者鎮痛反應（視覺模擬評分法VAS）、術中體動、術中呼吸抑製及術後噁心、嘔吐等不良反應的髮生率。結果兩組患者睫毛反射消失時間、胃腸鏡檢查時間比較差異無統計學意義（P ＞0.05）。觀察組患者的術畢清醒時間短，不良反應髮生率較對照組少，術中患者生命體徵更加平穩。結論地佐辛複閤丙泊酚靜脈痳醉用于無痛胃腸鏡檢查，鎮痛、鎮靜效果滿意，有較高的安全性，不良反應髮生率低，值得臨床推廣應用。
목적관찰지좌신복합병박분정맥마취용우무통위장경중적림상효과，탐토기안전성。방법선택100례ASAⅠ-Ⅱ급진행무통위장경검사환자수궤분위량조，관찰조（지좌신복합병박분정맥마취조）화대조조（분태니복합병박분정맥마취조）각50례。기록량조환자SPO2、HR、MAP、RR변화정황급의식소실시간（첩모반사소실시간）、술필청성시간、병박분용량급술필류관시간，관찰량조환자진통반응（시각모의평분법VAS）、술중체동、술중호흡억제급술후악심、구토등불량반응적발생솔。결과량조환자첩모반사소실시간、위장경검사시간비교차이무통계학의의（P ＞0.05）。관찰조환자적술필청성시간단，불량반응발생솔교대조조소，술중환자생명체정경가평은。결론지좌신복합병박분정맥마취용우무통위장경검사，진통、진정효과만의，유교고적안전성，불량반응발생솔저，치득림상추엄응용。
Objective Observation of dezocine combined with propofol intravenous anesthesia used in the clinical effect of painless gastrointestinal mirror, To study the safety. Method 100 cases of ASA Ⅰ- Ⅱwere randomly assigned patients with painless gastrointestinal endoscopy into two groups, The observation group (dezocine combined with propofol intravenous anesthesia group) and control group (fentanyl and propofol intravenous anesthesia group) with 50 cases in each. Two groups were recorded in SPO2, HR, MAP, RR changes and loss of consciousness (loss of eyelash reflex time), postoperative recovery time, the dosage of propofol and postoperative observation time, The two groups were observed the analgesic response (visual analogue scale, VAS) intraoperative body movement, intraoperative respiratory repression and postoperative nausea, vomiting and other adverse reaction rate. Results Two groups of patients with disappearance of eyelash reflex time, gastrointestinal endoscopy time had no significant difference (P >0.05). Observation of postoperative patients were awake time is short, the incidence of adverse reactions were less than those in the control group, the patients vital signs smoothly. Conclusion Dezocine combined with propofol intravenous anesthesia for painless gastrointestinal endoscopy, analgesic, sedative effect, high safety, low incidence of adverse reactions, it is worthy of clinical application.
