CAJ | 학술논문

目的探讨子宫大于12孕周的患者术前应用达菲林（注射用曲普瑞林3.75mg/支）后缩小子宫体积利于手术的临床应用价值。方法选取2009年1月~2013年1月在南海人民医院门诊行彩色多普勒超声诊断子宫超过12孕周大小的患者30例行腹腔镜下次全子宫切除术，以2009年1月~2010年12月术前未注射曲普瑞林施行手术的大子宫患者35例做对照组，2011年1月~2013年1月术前于月经周期第2d肌肉注射曲普瑞林3.75mg，1次/月，共3个月后行同样手术的为研究组。结果术前应用曲普瑞林的患者术中出血量少、手术时间短、出院时间短，与术前未应用曲普瑞林的患者差异有统计学意义。结论超过12孕周大小的子宫术前应用曲谱瑞林可减少子宫体积，减少子宫血流，使术中出血量明显下降。
목적탐토자궁대우12잉주적환자술전응용체비림（주사용곡보서림3.75mg/지）후축소자궁체적리우수술적림상응용개치。방법선취2009년1월~2013년1월재남해인민의원문진행채색다보륵초성진단자궁초과12잉주대소적환자30례행복강경하차전자궁절제술，이2009년1월~2010년12월술전미주사곡보서림시행수술적대자궁환자35례주대조조，2011년1월~2013년1월술전우월경주기제2d기육주사곡보서림3.75mg，1차/월，공3개월후행동양수술적위연구조。결과술전응용곡보서림적환자술중출혈량소、수술시간단、출원시간단，여술전미응용곡보서림적환자차이유통계학의의。결론초과12잉주대소적자궁술전응용곡보서림가감소자궁체적，감소자궁혈류，사술중출혈량명현하강。
Objective:To evaluate the clinical value of triptorelin (Injectable triptorelin 3.75mg/bot le), which can benefit the surgery by reducing the volume of uterus on patient with a uterus large than 12 weeks pregnancy. Methods: 33 patients with uteri larger than 12 weeks pregnancy which diagnosed by outpatient color Doppler ultrasound were selected in the case group. They were given intramuscular injection of 3.75mg triptorelin every second day of menstrual cycle for three months before they had laparoscopic panhysterectomy. 35 patients with same size of uteri were selected in the control group. They had laparoscopic panhysterectomy without injection of triptorelin. Results: The case group had less blood loss during panhysterectomy, shorter time of surgery, lower risk of fever, shorter hospital stay. The dif erence between case group and control group is statistical significant. Conclusion: Injection of triptorelin before performing surgery on uterus that is larger than 12 weeks pregnancy can reduce the volume of uterine, reduce the circulation of uterus, decrease the quantity of blood loss during surgery.