医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2013年
16期
204-204,205
,共2页
赛乐特%抑郁%焦虑%偏头痛
賽樂特%抑鬱%焦慮%偏頭痛
새악특%억욱%초필%편두통
Paroxetine%Depression%Anxiety%Migraine
目的探讨分析赛乐特治疗伴抑郁或焦虑的偏头痛临床疗效。方法选取我科（门诊和住院病房）于2012年1月~2013年5月收治的伴有抑郁或焦虑症状的偏头痛患者70例，按照随机数字分组法分为对照组和治疗组各35例，对照组患者给予西比灵5mg，1次/d；治疗组在对照组的基础上加用赛乐特20mg，1次/d，疗程为16w。结果治疗组的有效率为91.4%，显著高于对照组的74.29%，治疗组抑郁、焦虑缓解率明显高于对照组，头痛发作持续时间及发作次数显著低于对照组，两组比较P<0.05，差异具有统计学意义。治疗组症状轻微亚组达32例，显著多于对照组的14例，两组比较P<0.05，差异具有统计学意义。有肯定症状、症状重及症状极重亚组治疗组例数均明显少于对照组。两组比较P<0.05，差异具有统计学意义。结果表明治疗组患者抑郁、焦虑状态改善效果优于对照组。结论赛乐特治疗伴抑郁或焦虑的偏头痛临床疗效显著，值得推广应用。
目的探討分析賽樂特治療伴抑鬱或焦慮的偏頭痛臨床療效。方法選取我科（門診和住院病房）于2012年1月~2013年5月收治的伴有抑鬱或焦慮癥狀的偏頭痛患者70例，按照隨機數字分組法分為對照組和治療組各35例，對照組患者給予西比靈5mg，1次/d；治療組在對照組的基礎上加用賽樂特20mg，1次/d，療程為16w。結果治療組的有效率為91.4%，顯著高于對照組的74.29%，治療組抑鬱、焦慮緩解率明顯高于對照組，頭痛髮作持續時間及髮作次數顯著低于對照組，兩組比較P<0.05，差異具有統計學意義。治療組癥狀輕微亞組達32例，顯著多于對照組的14例，兩組比較P<0.05，差異具有統計學意義。有肯定癥狀、癥狀重及癥狀極重亞組治療組例數均明顯少于對照組。兩組比較P<0.05，差異具有統計學意義。結果錶明治療組患者抑鬱、焦慮狀態改善效果優于對照組。結論賽樂特治療伴抑鬱或焦慮的偏頭痛臨床療效顯著，值得推廣應用。
목적탐토분석새악특치료반억욱혹초필적편두통림상료효。방법선취아과（문진화주원병방）우2012년1월~2013년5월수치적반유억욱혹초필증상적편두통환자70례，안조수궤수자분조법분위대조조화치료조각35례，대조조환자급여서비령5mg，1차/d；치료조재대조조적기출상가용새악특20mg，1차/d，료정위16w。결과치료조적유효솔위91.4%，현저고우대조조적74.29%，치료조억욱、초필완해솔명현고우대조조，두통발작지속시간급발작차수현저저우대조조，량조비교P<0.05，차이구유통계학의의。치료조증상경미아조체32례，현저다우대조조적14례，량조비교P<0.05，차이구유통계학의의。유긍정증상、증상중급증상겁중아조치료조례수균명현소우대조조。량조비교P<0.05，차이구유통계학의의。결과표명치료조환자억욱、초필상태개선효과우우대조조。결론새악특치료반억욱혹초필적편두통림상료효현저，치득추엄응용。
Objective To investigate the clinical ef ect of Seroxat in the treatment of migraine with depression or anxiety. Methods Select our department (outpatient and inpatient wards) in January 2012 to May 2013 were treated with depression or anxiety symptoms of migraine suf erers in 70 cases,according to the random digit grouping divided into a control group and the treatment group 35 cases,the control group were treated with flunarizine 5mg, 1times/d;treatment group were based on the use of Seroxat 20mg,1times/d,treatment for 16weeks. Results The ef ective rate was 91.4%, significantly higher than the 74.29 percent in the treatment group depression,anxiety remission rate was significantly higher,headache duration and number of episodes was significantly lower than the control group,two groups, P<0.05,the dif erence was statistical y significant. Treatment group had mild symptoms subgroup of 32 patients was significantly bet er than the control group, 14 cases, the two groups P<0.05, statistical y significant dif erence. There are certainly symptoms,symptoms of heavy and very heavy symptom subgroups treated patients was significantly less than the control group. Two groups P<0.05,statistical y significant dif erence. The results showed that patients treated with depression, anxiety state improvement than the control group. Conclusion Treatment with Seroxat depression or anxiety, migraine significant clinical ef ect, should be widely applied.
