上海医药
上海醫藥
상해의약
SHANGHAI MEDICAL & PHARMACEUTICAL JOURNAL
2014年
9期
28-30
,共3页
血液透析%残余肾功能%透析充分性%钙磷代谢
血液透析%殘餘腎功能%透析充分性%鈣燐代謝
혈액투석%잔여신공능%투석충분성%개린대사
hemodialysis%residual renal function%dialysis adequacy%calcium-phosphorus metabolism
目的：探讨维持性血液透析患者残肾功能、透析充分性对钙磷代谢的影响。方法：选取上海市第六人民医院南院血液透析治疗中心2011年1月-2013年12月病例资料，共92例患者，235例次生化检验数据。血钙、血磷、iPTH分别与单室尿素清除率(spKt/V)、残余肾小球滤过率（GFR）作Pearson相关性分析，分别以spKt/V、GFR分组计算作t检验。结果：维持性血液透析患者血钙、血磷、iPTH与透析充分性无明显相关性(P>0.05)，血钙、血磷与残余肾功能有显著相关性(P<0.01)，iPTH与残余肾功能有相关性(P<0.05),血磷、iPTH相对于有无残余肾功能具有差异统计学意义(P<0.05)。结论：残余肾功能在血液透析患者钙磷代谢紊乱的纠正上具有重要作用，尤其在清除血磷中具有更积极的作用。
目的：探討維持性血液透析患者殘腎功能、透析充分性對鈣燐代謝的影響。方法：選取上海市第六人民醫院南院血液透析治療中心2011年1月-2013年12月病例資料，共92例患者，235例次生化檢驗數據。血鈣、血燐、iPTH分彆與單室尿素清除率(spKt/V)、殘餘腎小毬濾過率（GFR）作Pearson相關性分析，分彆以spKt/V、GFR分組計算作t檢驗。結果：維持性血液透析患者血鈣、血燐、iPTH與透析充分性無明顯相關性(P>0.05)，血鈣、血燐與殘餘腎功能有顯著相關性(P<0.01)，iPTH與殘餘腎功能有相關性(P<0.05),血燐、iPTH相對于有無殘餘腎功能具有差異統計學意義(P<0.05)。結論：殘餘腎功能在血液透析患者鈣燐代謝紊亂的糾正上具有重要作用，尤其在清除血燐中具有更積極的作用。
목적：탐토유지성혈액투석환자잔신공능、투석충분성대개린대사적영향。방법：선취상해시제륙인민의원남원혈액투석치료중심2011년1월-2013년12월병례자료，공92례환자，235례차생화검험수거。혈개、혈린、iPTH분별여단실뇨소청제솔(spKt/V)、잔여신소구려과솔（GFR）작Pearson상관성분석，분별이spKt/V、GFR분조계산작t검험。결과：유지성혈액투석환자혈개、혈린、iPTH여투석충분성무명현상관성(P>0.05)，혈개、혈린여잔여신공능유현저상관성(P<0.01)，iPTH여잔여신공능유상관성(P<0.05),혈린、iPTH상대우유무잔여신공능구유차이통계학의의(P<0.05)。결론：잔여신공능재혈액투석환자개린대사문란적규정상구유중요작용，우기재청제혈린중구유경적겁적작용。
Objective: To investigate the effect of maintenance hemodialysis and dialysis adequacy on the renal function of patients and calcium and phosphorus metabolism. Methods:Two hundred and thirty-ifve cases of biochemical test data involving 92 patients were selected at hemodialysis treatment center of Shanghai Sixth People’s Hospital during 2011-2013. Serum calcium and phosphorus, iPTH and single pool urea clearance rate (spKt/V), residual glomerular ifltration rate (GFR) for the Pearson correlation were analyzed by spKt/V, GFR grouping calculation for t test. Results:There was a signiifcant correlation in serum calcium, phosphorus with residual renal function (P<0.01) but not in serum calcium and phosphorus and iPTH with dialysis adequacy (P>0.05). There was a certain correlation between iPTH and residual renal function (P<0.05) and a statistically significant difference in phosphorus and iPTH with residual renal function (P<0.05). Conclusion: Residual renal function plays an important role in the disorders of calcium and phosphorus metabolism in hemodialysis patients and a more active role especially in the removal of serum phosphorus.
