CAJ | 학술논문

目的：观察金龙胶囊联合介入治疗对原发性肝癌患者免疫功能的调节作用。方法：随机选择经临床确诊为中晚期原发性肝癌的住院患者60例，随机分为观察组和对照组，观察组患者在介入治疗后第3天开始口服金龙胶囊，3次/日，4粒/次，30 d为1个疗程。对照组患者仅进行介入治疗。治疗过程中两组均不使用其他免疫调节剂。两组患者均于介入治疗前3～5d及介入治疗后1个月采集外周血标本检测细胞免疫功能指标。结果：观察组患者介入治疗后外周血CD3、CD4、NK细胞、CD4/CD8比值、SIL-2R和TSGF数量（均值）与治疗前均无显著变化。对照组患者介入治疗后外周血CD3、CD4、NK细胞、CD4/CD8比值、SIL-2R和TSGF数量（均值）较治疗前均显著降低（P<0.05）。结论：金龙胶囊有助于原发性肝癌患者介入治疗后细胞免疫功能的恢复。
목적：관찰금룡효낭연합개입치료대원발성간암환자면역공능적조절작용。방법：수궤선택경림상학진위중만기원발성간암적주원환자60례，수궤분위관찰조화대조조，관찰조환자재개입치료후제3천개시구복금룡효낭，3차/일，4립/차，30 d위1개료정。대조조환자부진행개입치료。치료과정중량조균불사용기타면역조절제。량조환자균우개입치료전3～5d급개입치료후1개월채집외주혈표본검측세포면역공능지표。결과：관찰조환자개입치료후외주혈CD3、CD4、NK세포、CD4/CD8비치、SIL-2R화TSGF수량（균치）여치료전균무현저변화。대조조환자개입치료후외주혈CD3、CD4、NK세포、CD4/CD8비치、SIL-2R화TSGF수량（균치）교치료전균현저강저（P<0.05）。결론：금룡효낭유조우원발성간암환자개입치료후세포면역공능적회복。
Objective:To determine the effects of Jinlong capsule combined with interventional therapy on the immune functions of primary hepatocellular carcinoma patients. Methods:Sixty randomly selected cases of clinically diagnosed primary hepatocellular carcinoma were divided into the observation group and the control group. Three days after operation, the observation group was given four Jinlong capsules three times a day for 30 days (one treatment). Meanwhile, the control group received interventional therapy after the operation. One to four days following one treatment, peripheral blood specimens were collected from the two groups to determine the cellular immune function indices. Results:The cell numbers (mean) of the peripheral blood components CD3, CD4, NK, SIL-2R, TSGF, and SIL-2R and the CD4/CD8 ratio in the observation group showed no significant difference before and after treatment. In the control group, these indices were significantly different before and after treatment. Conclusion:The Jinlong capsule facilitates the cellu-lar immunity recovery of patients with primary hepatocellular carcinoma after interventional therapy.