CAJ | 학술논문

目的：探讨磁敏感加权成像(susceptibility weighted imaging,SWI)对缺血性脑卒中出血性转化(hemorrhagic transfor-mation,HT)的预测价值。方法选取48例缺血性脑卒中患者为研究对象,观察 HT 在 CT、T1 WI、DWI 及 SWI 图像中的影像表现,以及 SWI图像小静脉异常显示及脑微出血(cerebral microbleeds,CMBs)的分布和信号特点,并分析其与 HT 的关系。结果本组48例患者中,共19例(39.6%)发生 HT,T1 WI、DWI、SWI检测 HT的敏感度分别为68.4%、36.8%和100%。梗死灶周围小静脉异常显示与 HT的发生具有显著相关性(P=0.001)。随CMBs程度加重,HT的发生率大大增加。结论 SWI可较敏感地预测 HT的发生,有助于缺血性脑卒中临床治疗策略的制定。
목적：탐토자민감가권성상(susceptibility weighted imaging,SWI)대결혈성뇌졸중출혈성전화(hemorrhagic transfor-mation,HT)적예측개치。방법선취48례결혈성뇌졸중환자위연구대상,관찰 HT 재 CT、T1 WI、DWI 급 SWI 도상중적영상표현,이급 SWI도상소정맥이상현시급뇌미출혈(cerebral microbleeds,CMBs)적분포화신호특점,병분석기여 HT 적관계。결과본조48례환자중,공19례(39.6%)발생 HT,T1 WI、DWI、SWI검측 HT적민감도분별위68.4%、36.8%화100%。경사조주위소정맥이상현시여 HT적발생구유현저상관성(P=0.001)。수CMBs정도가중,HT적발생솔대대증가。결론 SWI가교민감지예측 HT적발생,유조우결혈성뇌졸중림상치료책략적제정。
Objective To investigate the predictable value of susceptibility weighted imaging (SWI)in hemorrhagic transforma-tion (HT)of ischemic stroke.Methods 48 patients with ischemic stroke were involved.The presence and features of HT on CT, T1 WI,DWI and SWI were observed,as well as the distribution and signal features of cerebral microbleeds (CMBs),abnormal visi-bility of venules on SWI sequence.The correlation between those imaging findings and HT were analyzed.Results HT was detected in 19 of 48 patients (39.6%).The sensibility of T1 WI,DWI,SWI in detecting HT were 68.4%,36.8%,100%,respectively.HT was significantly associated with abnormal visibility of venules within the infarction region.The incidence of HT greatly increased with the aggravation of CMBs.Conclusion SWI can be a sensitive predictor for HT,and it’s helpful in making clinical strategy for ischemic stroke.