CAJ | 학술논문

目的：探寻注射曲普瑞林剧烈疼痛的原因，提出减轻疼痛的对策。方法：选择接受体外受精-胚胎移植中采用注射0．05 mg/次曲普瑞林注射的长方案患者，将自冰箱内取出的药液立即进行注射者设为对照组，将药液取出后行合理复温再进行注射为实验组，注射后分别进行疼痛评分，并记录疼痛持续时间，并记录相关温度变化。结果：实验组疼痛评分明显降低，疼痛时间明显减少，具有显著性差异（P＜0．05）。2组在获卵率、受精率、妊娠率均无明显差异（P＞0．05）。结论：低温存放曲普瑞林注射是引起疼痛的重要原因，将药液合理提温是减轻疼痛安全有效的方法。
목적：탐심주사곡보서림극렬동통적원인，제출감경동통적대책。방법：선택접수체외수정-배태이식중채용주사0．05 mg/차곡보서림주사적장방안환자，장자빙상내취출적약액립즉진행주사자설위대조조，장약액취출후행합리복온재진행주사위실험조，주사후분별진행동통평분，병기록동통지속시간，병기록상관온도변화。결과：실험조동통평분명현강저，동통시간명현감소，구유현저성차이（P＜0．05）。2조재획란솔、수정솔、임신솔균무명현차이（P＞0．05）。결론：저온존방곡보서림주사시인기동통적중요원인，장약액합리제온시감경동통안전유효적방법。
Objective:To investigate the causes of severe pain from Triptorelin injection , and to propose the relieve measures .Meth-ods:A database was analyzed retrospectively concerning cycles performed Triptorelin injection (0.05mg) in GnRH-agonist long protocol in vitro fertilization-embryo transfer ( IVF-ET) .Cycles performed immediate injections from the refrigerator were grouped as the control group .Cycles performed the rewarming liquid injections were grouped as the experimental group .Assess the pain levels after injection , re-cord the pain duration and measure the related temperature changes .Results:Pain level and duration in experimental group was signifi-cantly reduced, with a very significant difference (P<0.05).The two groups were not significantly different (P>0.05) in oocytes, fer-tilization, and pregnancy rate .Conclusion:Low temperature storage is the significant reason for Triptorelin injection pain .Implementing reasonable rewarming is a safe and effective way to relieve pain .