CAJ | 학술논문

目的通过观察心脏死亡器官捐献（Donation after Cardiac Death，DCD）移植器官的临床结果，探讨DCD移植的可行性和注意事项。方法对华中科技大学同济医学院附属同济医院2010年3月至2012年10月期间施行的DCD移植器官的临床资料进行回顾性总结。结果共有13例受者纳入研究，包括8例肾移植和5例肝移植，手术顺利。肾移植病例中术后分别因移植肾动脉破裂、急性抗体介导的排斥反应（AAMR）而切除移植肾2例，因脑血管意外死亡1例。肝移植病例中因肝动脉出血死亡1例。总体1年移植物/人存活率分别为69.2%和84.6%。结论使用DCD捐献器官可以扩大供体来源，缓解器官短缺困难，但应注意并发症发生，提高移植效果。
목적통과관찰심장사망기관연헌（Donation after Cardiac Death，DCD）이식기관적림상결과，탐토DCD이식적가행성화주의사항。방법대화중과기대학동제의학원부속동제의원2010년3월지2012년10월기간시행적DCD이식기관적림상자료진행회고성총결。결과공유13례수자납입연구，포괄8례신이식화5례간이식，수술순리。신이식병례중술후분별인이식신동맥파렬、급성항체개도적배척반응（AAMR）이절제이식신2례，인뇌혈관의외사망1례。간이식병례중인간동맥출혈사망1례。총체1년이식물/인존활솔분별위69.2%화84.6%。결론사용DCD연헌기관가이확대공체래원，완해기관단결곤난，단응주의병발증발생，제고이식효과。
Objective To investigate the feasibility and precautions of donation after cardiac death (DCD),clinical data of organ transplantations using DCD donors were analyzed. Methods We retrospectively reviewed the clinical data of organ transplantations using DCD donors in Tongji Hospital of Tongji Medical College of Huazhong University of Science&Technology from March 2010 to October 2012. Results There were totally 13 recipients in this study,including 8 kidney transplants and 5 liver transplants,2 renal grafts were resected because of renal graft artery rupture and acute antibody-mediated rejection respectively,1 kidney transplant recipients died of cerebrovascular accident,1 liver transplant recipient died of hepatic artery rupture. Totally 1-year graft/recipient survival was 69.2% and 84.6% respectively. Conclusion Donor source can be expanded with DCD donors,the occurrence of complications should be paid attention to and the effects of DCD transplantation should be improved.