中外女性健康（下半月）
中外女性健康（下半月）
중외녀성건강（하반월）
CHINESE-FOREIGN WOMEN'S HEALTH
2013年
4期
6-7
,共2页
人性化护理%ICU%应用
人性化護理%ICU%應用
인성화호리%ICU%응용
MCV%MCH%Hemoglobin Electrophoresis%Mediterranean anemia gene
目的：探讨地中海贫血基因检测在地中海贫血筛查诊断中的应用价值。方法：对地贫调查中的1354例小学生进行血液常规检测、血红蛋白电泳和地中海贫血基因检测，统计分析三种筛查诊断方法的关系。结果：以MCV≤80fl为标准筛查地贫，α地贫的漏诊率为35.87%，β地贫漏诊率为6.74%；以MCH≤25pg为筛查标准，α地贫漏诊率为38.48%，β地贫漏诊率为15.28%；以MCV≤80fl、MCH≤25pg联合为筛查标准，α地贫漏诊率为29.26%，β地贫漏诊率为5.96%；以血红蛋白电泳HbA2＞3.5%为筛查标准，β地贫漏诊率为0.26%，发出现快速区带筛查α地贫漏诊率为98.00%。结论：MCV、MCH和血红蛋白电泳可作为地贫筛查的一种简单、方便、快速的方法，但不能作为金标准，地中海贫血基因检测在优生优育指导中起着不可替代的重要作用。
目的：探討地中海貧血基因檢測在地中海貧血篩查診斷中的應用價值。方法：對地貧調查中的1354例小學生進行血液常規檢測、血紅蛋白電泳和地中海貧血基因檢測，統計分析三種篩查診斷方法的關繫。結果：以MCV≤80fl為標準篩查地貧，α地貧的漏診率為35.87%，β地貧漏診率為6.74%；以MCH≤25pg為篩查標準，α地貧漏診率為38.48%，β地貧漏診率為15.28%；以MCV≤80fl、MCH≤25pg聯閤為篩查標準，α地貧漏診率為29.26%，β地貧漏診率為5.96%；以血紅蛋白電泳HbA2＞3.5%為篩查標準，β地貧漏診率為0.26%，髮齣現快速區帶篩查α地貧漏診率為98.00%。結論：MCV、MCH和血紅蛋白電泳可作為地貧篩查的一種簡單、方便、快速的方法，但不能作為金標準，地中海貧血基因檢測在優生優育指導中起著不可替代的重要作用。
목적：탐토지중해빈혈기인검측재지중해빈혈사사진단중적응용개치。방법：대지빈조사중적1354례소학생진행혈액상규검측、혈홍단백전영화지중해빈혈기인검측，통계분석삼충사사진단방법적관계。결과：이MCV≤80fl위표준사사지빈，α지빈적루진솔위35.87%，β지빈루진솔위6.74%；이MCH≤25pg위사사표준，α지빈루진솔위38.48%，β지빈루진솔위15.28%；이MCV≤80fl、MCH≤25pg연합위사사표준，α지빈루진솔위29.26%，β지빈루진솔위5.96%；이혈홍단백전영HbA2＞3.5%위사사표준，β지빈루진솔위0.26%，발출현쾌속구대사사α지빈루진솔위98.00%。결론：MCV、MCH화혈홍단백전영가작위지빈사사적일충간단、방편、쾌속적방법，단불능작위금표준，지중해빈혈기인검측재우생우육지도중기착불가체대적중요작용。
Objective: Discuss the Mediterranean anemia gene detection in the diagnosis of the Mediterranean anemia screening application value. Method: Of the Mediterranean anemia’s survey 1354 cases of primary school students to proceed blood routine detection、hemoglobin electrophoresis and Mediterranean anemia gene test, statistical analysis of three kinds of screening diagnosis method of the relationship. Result: According to the MCV 80 fl or less Mediterranean anemia for standard screening, αMediterranean anemia missed diagnosis rate was 35.87%,βMediterranean anemia missed diagnosis rate was 6.74%;In MCH 25 pg or less for screening criteria, αMediterranean anemia missed diagnosis rate was 38.48%, β Mediterranean anemia missed diagnosis rate was 15.28%;With the MCV80 fl, MCH 25 pg or less joint criteria for screening,αMediterranean anemia missed diagnosis rate was 29.26%,βMediterranean anemia missed diagnosis rate was 5.96%;By hemoglobin electrophoresis HbA2>3.5%for screening criteria,β Mediterranean anemia missed diagnosis rate was 0.26%, send a quick zone screening α Mediterranean anemia missed diagnosis rate was 98.00%. Conclusion:The MCV, MCH and hemoglobin electrophoresis can be used as the Mediterranean anemia screening method of a kind of simple、convenient、fast, but not as a gold standard, the Mediterranean anemia gene testing detects in guidance of eugenic and superior nurture plays an irreplaceable important role.
