CAJ | 학술논문

背景：世界各地关于进食障碍的流行病学研究得到的患病率数据不尽一致，目前尚缺乏系统综述研究以明确这些差别的原因所在。目的：运用Meta分析的方法汇总不同地区普通人群进食障碍的患病率数据，以确定与患病率相关的因素。方法：系统检索PubMed/Medline、PsycINFO、ISI web of knowledge、Ovid、中国知识资源总库，中国科技期刊数据库，万方数据，中国生物医学文献服务系统的数据库，收集关于进食障碍患病率的文献，按照预先制定的纳入及排除标准筛选相关研究。采用R-2.15.2软件进行统计分析。结果：共检索到9315篇不重复的文献（约四分之一为中文文献），其中仅15项研究符合纳入标准，累计调查72961人。纳入的15项中无国内研究，仅一项来自于亚洲国家（韩国）。估计的进食障碍的终生患病率为1.01%（95%CI，0.54～1.89%），12个月患病率为0.37%（95%CI，0.22～0.63%），4周患病率为0.21%（95%CI，0.15～0.28%）。神经性厌食、神经性贪食、暴食性障碍的终生患病率分别为0.21%（95%CI，0.11～0.38%）、0.81%（95%CI，0.59～1.09%）、2.22%（95%CI，1.78～2.76%）。女性进食障碍终生患病率与男性之比为4.2。欧洲国家进食障碍的终生患病率约为韩国研究报告数据的6.1倍。随着时间推移，总的进食障碍患病率有所升高，但无统计学意义，但神经性厌食症的患病率有统计学意义的升高。结论：普通人群中进食障碍较为常见，女性比男性多，西方国家比亚洲国家多。可能由于进食障碍的诊断标准有了变动，近年来报道的患病率有增高趋势。研究局限性包括可获得的流行病学资料非常有限，不同研究中进食障碍包括的类别有所不同以及缺少中低收入国家（包括中国）中合适的流行病学研究。
배경：세계각지관우진식장애적류행병학연구득도적환병솔수거불진일치，목전상결핍계통종술연구이명학저사차별적원인소재。목적：운용Meta분석적방법회총불동지구보통인군진식장애적환병솔수거，이학정여환병솔상관적인소。방법：계통검색PubMed/Medline、PsycINFO、ISI web of knowledge、Ovid、중국지식자원총고，중국과기기간수거고，만방수거，중국생물의학문헌복무계통적수거고，수집관우진식장애환병솔적문헌，안조예선제정적납입급배제표준사선상관연구。채용R-2.15.2연건진행통계분석。결과：공검색도9315편불중복적문헌（약사분지일위중문문헌），기중부15항연구부합납입표준，루계조사72961인。납입적15항중무국내연구，부일항래자우아주국가（한국）。고계적진식장애적종생환병솔위1.01%（95%CI，0.54～1.89%），12개월환병솔위0.37%（95%CI，0.22～0.63%），4주환병솔위0.21%（95%CI，0.15～0.28%）。신경성염식、신경성탐식、폭식성장애적종생환병솔분별위0.21%（95%CI，0.11～0.38%）、0.81%（95%CI，0.59～1.09%）、2.22%（95%CI，1.78～2.76%）。녀성진식장애종생환병솔여남성지비위4.2。구주국가진식장애적종생환병솔약위한국연구보고수거적6.1배。수착시간추이，총적진식장애환병솔유소승고，단무통계학의의，단신경성염식증적환병솔유통계학의의적승고。결론：보통인군중진식장애교위상견，녀성비남성다，서방국가비아주국가다。가능유우진식장애적진단표준유료변동，근년래보도적환병솔유증고추세。연구국한성포괄가획득적류행병학자료비상유한，불동연구중진식장애포괄적유별유소불동이급결소중저수입국가（포괄중국）중합괄적류행병학연구。
Background:The estimated prevalence of eating disorders reported in community surveys from different parts of the world varies widely but there has been no systematic attempt to identify the reasons for these differences. Objective:Use meta-analysis methods to pool data from community surveys about the prevalence of eating disorders in different locations and to identify the factors that are associated with the reported prevalence of eating disorders. Methods:Based on pre-defined inclusion and exclusion criteria, studies were identified from the following databases: PubMed/Medline, PsycINFO, ISI web of knowledge, Ovid, Chinese National Knowledge Infrastructure, Chongqing VIP database for Chinese Technical Periodicals, WANFANG DATA, and Chinese Biological Literature Service System. Statistical analysis was conducted using R software. Results:Among the 9315 unduplicated reports reviewed (one-fourth of which were published in Chinese) only 15-with a pooled sample size of 72,961 individuals-met the inclusion criteria for the analysis. None of the included studies were from China and only one Asian country (South Korea) was included in the analysis. The estimated lifetime prevalence, 12-month prevalence, and 4-week prevalence of any eating disorder was 1.01%(95%confidence interval [CI], 0.54-1.89), 0.37%(CI, 0.22-0.63), and 0.21%(CI, 0.15-0.28), respectively. Estimated lifetime prevalence of anorexia nervosa, bulimia nervosa, and binge eating disorder was 0.21%(CI, 0.11-0.38), 0.81%(CI, 0.59-1.09), and 2.22%(CI, 1.78-2.76), respectively. The estimated female-male ratio for lifetime prevalence of any eating disorder was 4.2. The lifetime prevalence of any eating disorder reported from studies conducted in Western countries was 6.1-fold greater than that reported in a single study from South Korea. Over time there has been a non-significant increase in reported prevalence of any eating disorder and a significant increase in reported prevalence of anorexia nervosa. Conclusions:Eating disorders are common in the general population, more common in women than men, and more common in Western countries than in Asian countries.The reported prevalence is increasing over time, but this may be due to changes in diagnostic criteria. There are serious limitations in the available epidemiological data, primarily differences in the conditions included among eating disorders and the lack of acceptable epidemiological studies from low-and middle-income countries (including China).