医学检验与临床
醫學檢驗與臨床
의학검험여림상
MEDICAL LATORATORY SCIENCE AND CLINICES
2013年
4期
43-45
,共3页
肛周脓肿%细菌学检验%耐药性
肛週膿腫%細菌學檢驗%耐藥性
항주농종%세균학검험%내약성
Perianal abscess%Bacteriological examination%Drug resistance
目的：探讨佛山市中医院肛周脓肿患者脓液需氧菌的菌群分布及药敏特征，动态观察其主要病原菌对抗菌药物的耐药变化特点。方法：对该院2006-2011年肛肠科送检的首次入院病人的肛周脓肿患者脓液标本进行常规微生物培养鉴定和药敏试验并统计分析。结果：2006-2011年从肛周脓肿患者脓液中共检出需氧菌299株，以革兰阴性菌为主（79.6%），其中大肠埃希菌居首位（58.5%），其次为肺炎克雷伯菌（12.0%）；革兰阳性菌以链球菌为主（10.7%），其次是金黄色葡萄球菌（2.7%）。大肠埃希菌和肺炎克雷伯菌对亚胺培南、头孢西丁和阿米卡星敏感性较高；万古霉素、青霉素G和左氧氟沙星对链球菌敏感性较高。金黄色葡萄球菌全对复方新诺明、万古霉素、左氧氟沙星、苯唑西林和米诺环素100%敏感，而对青霉素100%耐药。大肠埃希菌产ESBLs的检出率呈波动性变化，总体呈缓慢上升态势。结论：肛周脓肿患者脓液标本需氧菌以大肠埃希菌占首位，其多重耐药处于上升态势，需氧菌中各病原菌对抗菌药物的敏感性差异较大。临床应重视标本送检，不可忽视厌氧菌的培养。
目的：探討彿山市中醫院肛週膿腫患者膿液需氧菌的菌群分佈及藥敏特徵，動態觀察其主要病原菌對抗菌藥物的耐藥變化特點。方法：對該院2006-2011年肛腸科送檢的首次入院病人的肛週膿腫患者膿液標本進行常規微生物培養鑒定和藥敏試驗併統計分析。結果：2006-2011年從肛週膿腫患者膿液中共檢齣需氧菌299株，以革蘭陰性菌為主（79.6%），其中大腸埃希菌居首位（58.5%），其次為肺炎剋雷伯菌（12.0%）；革蘭暘性菌以鏈毬菌為主（10.7%），其次是金黃色葡萄毬菌（2.7%）。大腸埃希菌和肺炎剋雷伯菌對亞胺培南、頭孢西丁和阿米卡星敏感性較高；萬古黴素、青黴素G和左氧氟沙星對鏈毬菌敏感性較高。金黃色葡萄毬菌全對複方新諾明、萬古黴素、左氧氟沙星、苯唑西林和米諾環素100%敏感，而對青黴素100%耐藥。大腸埃希菌產ESBLs的檢齣率呈波動性變化，總體呈緩慢上升態勢。結論：肛週膿腫患者膿液標本需氧菌以大腸埃希菌佔首位，其多重耐藥處于上升態勢，需氧菌中各病原菌對抗菌藥物的敏感性差異較大。臨床應重視標本送檢，不可忽視厭氧菌的培養。
목적：탐토불산시중의원항주농종환자농액수양균적균군분포급약민특정，동태관찰기주요병원균대항균약물적내약변화특점。방법：대해원2006-2011년항장과송검적수차입원병인적항주농종환자농액표본진행상규미생물배양감정화약민시험병통계분석。결과：2006-2011년종항주농종환자농액중공검출수양균299주，이혁란음성균위주（79.6%），기중대장애희균거수위（58.5%），기차위폐염극뢰백균（12.0%）；혁란양성균이련구균위주（10.7%），기차시금황색포도구균（2.7%）。대장애희균화폐염극뢰백균대아알배남、두포서정화아미잡성민감성교고；만고매소、청매소G화좌양불사성대련구균민감성교고。금황색포도구균전대복방신낙명、만고매소、좌양불사성、분서서림화미낙배소100%민감，이대청매소100%내약。대장애희균산ESBLs적검출솔정파동성변화，총체정완만상승태세。결론：항주농종환자농액표본수양균이대장애희균점수위，기다중내약처우상승태세，수양균중각병원균대항균약물적민감성차이교대。림상응중시표본송검，불가홀시염양균적배양。
Objective:To explore the distribution and drug resistance of aerobic flora in patients with perianal abscess recruited from Hospital of Foshan City, Guangdong Province. Additionally, to observe dynamic changes of the main pathogens in regards to antimicrobial drug resistance. Methods:From 2006 to 2011, a total of 100 hospitalized patients with perianal abscesses were recruited from the Hospital of Foshan City for this study. Pus specimens were collected for routine microbiological culture identification and drug susceptibility testing and the results were analyzed using the student T test.Results:A total of 299 aerobic bacteria strains were detected in patients with perianal abscess pus, mainly Gram-negative bacteria (79.6%), which ranks first in Escherichia coli (58.5%), followed by Klebsiella pneumoniae andReber bacteria (12.0%);Also found were Gram-positive bacteria, led bystreptococcus (10.7%) and Staphylococcus aureus (2.7%). Escherichia coli and Klebsiella pneumoniae have a higher sensitivity to Imipenem, cefoxitin, and amikacin. Streptococcus has a high sensitivity to vancomycin, penicillin G and levofloxacin. Notably, Staphylococcus aureus has 100%sensitivity to cotrimoxazole, vancomycin, levofloxacin, oxacillin, and minocycline and is 100%resistant to penicillin. The detection rate of ESBLs in Escherichia coli fluctuated, although a slow upward trend showed, overall.Conclusions:Aerobic Escherichia coli is the dominant strain detected in patients with perianal abscess pus. The increase of multiple drug resistance and the sensitivity of pathogenic aerobic bacteria to antimicrobial agents differ. Much attention should be paid to the detection of these pathogens in clinical specimens and the cultivation of the anaerobic bacteria should be included.
