CAJ | 학술논문

目的：探讨冠心病痰瘀证与多个客观指标的相关性，为冠心病痰瘀证的临床研究提供依据。方法：将120例冠心病患者分为痰瘀证组（76例）和非痰瘀证组（44例），另选择体检健康者20例设为正常对照组，从血脂、糖代谢、炎症因子等方面进行比较和统计学分析。结果：痰瘀证组在总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）、血胰岛素（FINS）、超敏 C 反应蛋白（hs-CRP）、基质金属蛋白酶-9（MMP-9）水平方面均明显高于正常对照组及非痰瘀证组（P<0.05或 P<0.01）。结论：TC、TG、LDL-C、FINS、hs-CRP、MMP-9水平可为冠心病痰瘀辨证分型提供客观依据。
목적：탐토관심병담어증여다개객관지표적상관성，위관심병담어증적림상연구제공의거。방법：장120례관심병환자분위담어증조（76례）화비담어증조（44례），령선택체검건강자20례설위정상대조조，종혈지、당대사、염증인자등방면진행비교화통계학분석。결과：담어증조재총담고순（TC）、감유삼지（TG）、저밀도지단백담고순（LDL-C）、혈이도소（FINS）、초민 C 반응단백（hs-CRP）、기질금속단백매-9（MMP-9）수평방면균명현고우정상대조조급비담어증조（P<0.05혹 P<0.01）。결론：TC、TG、LDL-C、FINS、hs-CRP、MMP-9수평가위관심병담어변증분형제공객관의거。
This study was aimed to explore the correlation between the phlegm-stasis syndrome of coronary heart disease ( CHD ) and multiple objective indexes in order to provide the basis for clinical study of phlegm-stasis syndrome of CHD . A total of 120 patients were divided into the phlegm-stasis syndrome group ( 76 cases ) and the non-phlegm-stasis syndrome group ( 44 cases ) . And 20 cases of healthy volunteers were selected as the normal control group . Comparison and statistical analysis were made from aspects of blood lipids , glucose metabolism , inflammation factor and etc . The results showed that the levels of total cholesterol ( TC ) , triglyceride ( TG ) , low density lipoprotein cholesterol ( LDL-C ) , fasting insulin ( FINS ) , hypersensitive C-reactive protein ( hs-CRP ) , matrix metalloproteinase-9 ( MMP-9 ) in the phlegm-stasis syndrome group were significantly higher than those in the normal control group and the non-phlegm-stasis syndrome group ( P <0.05, or P < 0.01). It was concluded that the levels of TC, TG, LDL-C, FINS, hs-CRP and MMP-9 can provide objective basis for the phlegm-stasis syndrome of CHD .