创伤外科杂志
創傷外科雜誌
창상외과잡지
JOURNAL OF AUMATIC SURGERY
2013年
5期
430-433
,共4页
邓永兵%肖虹%胡晞%刘科
鄧永兵%肖虹%鬍晞%劉科
산영병%초홍%호희%류과
颅脑损伤%静脉血栓%低分子肝素%气压治疗
顱腦損傷%靜脈血栓%低分子肝素%氣壓治療
로뇌손상%정맥혈전%저분자간소%기압치료
brain injury%venous thrombosis%low molecular-weight heparin%pneumatic compression
目的探讨低分子肝素、间歇性气压治疗对颅脑创伤患者下肢深静脉血栓( DVT)形成的预防效果。方法回顾分析我科2010年3月~2013年3月682例颅脑创伤患者临床资料。有148例应用低分子肝素( LMWH)药物预防;173例行间歇性气压治疗( IPC)物理预防;169例行LMWH、IPC联合预防;有192例未实施LMWH、IPC预防。下肢深静脉彩超或下肢CTV诊断DVT。结果 LMWH药物预防组,DVT 19例(12.83%); IPC预防组,DVT 23例(13.29%); LMWH、IPC联合预防组,DVT 14例(8.28%);未实施LMWH、IPC预防组,DVT 38例(19.80%)。 LMWH、IPC联合预防组、LMWH预防组、IPC预防组DVT发生率明显低于未实施LMWH、IPC预防组(P<0.05); LMWH、IPC联合预防组DVT发生率明显低于LMWH预防组或IPC物理预防组( P<0.05)。结论 LMWH、IPC对预防颅脑创伤患者下肢深静脉血栓形成有一定的临床疗效,且LMWH、IPC联合预防效果更好。
目的探討低分子肝素、間歇性氣壓治療對顱腦創傷患者下肢深靜脈血栓( DVT)形成的預防效果。方法迴顧分析我科2010年3月~2013年3月682例顱腦創傷患者臨床資料。有148例應用低分子肝素( LMWH)藥物預防;173例行間歇性氣壓治療( IPC)物理預防;169例行LMWH、IPC聯閤預防;有192例未實施LMWH、IPC預防。下肢深靜脈綵超或下肢CTV診斷DVT。結果 LMWH藥物預防組,DVT 19例(12.83%); IPC預防組,DVT 23例(13.29%); LMWH、IPC聯閤預防組,DVT 14例(8.28%);未實施LMWH、IPC預防組,DVT 38例(19.80%)。 LMWH、IPC聯閤預防組、LMWH預防組、IPC預防組DVT髮生率明顯低于未實施LMWH、IPC預防組(P<0.05); LMWH、IPC聯閤預防組DVT髮生率明顯低于LMWH預防組或IPC物理預防組( P<0.05)。結論 LMWH、IPC對預防顱腦創傷患者下肢深靜脈血栓形成有一定的臨床療效,且LMWH、IPC聯閤預防效果更好。
목적탐토저분자간소、간헐성기압치료대로뇌창상환자하지심정맥혈전( DVT)형성적예방효과。방법회고분석아과2010년3월~2013년3월682례로뇌창상환자림상자료。유148례응용저분자간소( LMWH)약물예방;173례행간헐성기압치료( IPC)물리예방;169례행LMWH、IPC연합예방;유192례미실시LMWH、IPC예방。하지심정맥채초혹하지CTV진단DVT。결과 LMWH약물예방조,DVT 19례(12.83%); IPC예방조,DVT 23례(13.29%); LMWH、IPC연합예방조,DVT 14례(8.28%);미실시LMWH、IPC예방조,DVT 38례(19.80%)。 LMWH、IPC연합예방조、LMWH예방조、IPC예방조DVT발생솔명현저우미실시LMWH、IPC예방조(P<0.05); LMWH、IPC연합예방조DVT발생솔명현저우LMWH예방조혹IPC물리예방조( P<0.05)。결론 LMWH、IPC대예방로뇌창상환자하지심정맥혈전형성유일정적림상료효,차LMWH、IPC연합예방효과경호。
Objective To explore the efficacy and safety of low molecular -weight heparin ( LMWH) and intermittent pneumatic compression ( IPC) against deep venous thrombosis ( DVT) following traumatic brain injury (TBI).Methods The clinical data of 682 patients with TBI from Mar.2010 to Mar.2013 were analyzed retro-spectively.In those cases,148 cases received LMWH injection,173 cases received IPC prevention,169 cases re-ceived LMWH and IPC ,192 cases did not receive LMWH or IPC prevention .DVT was diagnosed by color duplex ultrasonography or computed tomo-venography(CTV).Results There were 19 cases of DVT (12.83%),23 cases of DVT (13.29%),14 cases of DVT (8.28%) and 38 cases of DVT (19.80%) in the group of LMWH preven-tion,group of IPC prevention,group of LMWH+IPC prevention and group of non-preventive measure,respectively. The incidence of DVT in group 1,2 and 3 was significantly lower than that in group 4 (P<0.05).The incidence of DVT in group 3 was significantly lower than that in group 1 or 2(P<0.05).Conclusion LMWH and IPC are ef-fective in preventing DVT following TBI .Meanwhile ,application of LMWH in combined with IPC can achieve better efficacy.