CAJ | 학술논문

目的探讨振动反应成像（VRI）在老年慢性阻塞性肺疾病（COPD）患者疗效评估中的应用价值。方法2012年1月至6月在南京医科大学附属南京医院（南京市第一医院）呼吸科住院的41例老年COPD急性加重期患者在治疗前后进行呼吸困难分级、动脉血气、肺功能和VRI检查。结果治疗后患者的呼吸困难评分显著降低[（3.46±0.87） vs （2.17±0.80），P＜0.01]，动脉血气PaO2明显提高、肺功能改善。治疗后VRI图像明显改善，振动曲线异常评分由（3.61±1.09）降至[（2.85±1.26）， P＜0.01]，动态图像异常评分由（10.54±2.91）降至[（6.15±2.23），P＜0.01]，肺部啰音数从（9.98±7.51）减少至[（3.15±4.44）， P＜0.01]。结论 VRI可用于动态监测和评估老年COPD患者的疗效。
목적탐토진동반응성상（VRI）재노년만성조새성폐질병（COPD）환자료효평고중적응용개치。방법2012년1월지6월재남경의과대학부속남경의원（남경시제일의원）호흡과주원적41례노년COPD급성가중기환자재치료전후진행호흡곤난분급、동맥혈기、폐공능화VRI검사。결과치료후환자적호흡곤난평분현저강저[（3.46±0.87） vs （2.17±0.80），P＜0.01]，동맥혈기PaO2명현제고、폐공능개선。치료후VRI도상명현개선，진동곡선이상평분유（3.61±1.09）강지[（2.85±1.26）， P＜0.01]，동태도상이상평분유（10.54±2.91）강지[（6.15±2.23），P＜0.01]，폐부라음수종（9.98±7.51）감소지[（3.15±4.44）， P＜0.01]。결론 VRI가용우동태감측화평고노년COPD환자적료효。
Objective To investigate the value of vibration response imaging (VRI) in the assessment and monitoring of therapeutic efficiency of chronic obstructive pulmonary disease (COPD) in the elderly patients. Methods A total of 41 patients (over 60 years old) with acute exacerbations of COPD hospitalized in our department from January to June 2012 were recruited in this study. Dyspnea score, arterial blood gases analysis, lung function test and VRI were performed on them before and after treatment. Results Dyspnea grade was significantly reduced after treatment [(3.46±0.87) vs (2.17±0.80), P<0.01]. PaO2, lung function and VRI results were improved significantly after treatment. Dynamic image grades were reduced from (3.61±1.09) to (2.85±1.26) (P<0.01), graph grades from (10.54±2.91) to (6.15±2.23) (P<0.01), and crack counts from (9.98±7.51) to (3.15±4.44) (P<0.01). Conclusion VRI is helpful in the assessment and monitoring of therapeutic efficiency of COPD in elderly patients.