CAJ | 학술논문

胎儿炎症反应综合征（FIRS）是指胎儿免疫系统被激活释放大量致炎因子而导致的一种亚临床状态，是全身炎症反应综合征（SIRS）在胎儿期的特殊表现形式。宫内感染是导致FIRS的最常见病因。FIRS与早产、早产儿脑白质损伤、支气管肺发育不良、新生儿坏死性小肠结肠炎等多种新生儿疾病的发生密切相关。
태인염증반응종합정（FIRS）시지태인면역계통피격활석방대량치염인자이도치적일충아림상상태，시전신염증반응종합정（SIRS）재태인기적특수표현형식。궁내감염시도치FIRS적최상견병인。FIRS여조산、조산인뇌백질손상、지기관폐발육불량、신생인배사성소장결장염등다충신생인질병적발생밀절상관。
The fetal inlfammatory response syndrome (FIRS) is a subclinical condition characterized by systemic acti-vation of the fetal innate immune system with a large number of pro-inlfammatory cytokines released. FIRS is the fetal coun-terpart of the systemic inlfammatory response syndrome (SIRS) described in adults. Intrauterine infection is the most common reason of FIRS. FIRS has been implicated as a cause of preterm labor, preterm white matter injury, bronchopulmonary dyspla-sia (BPD) and necrotizing enterocolitis (NEC).