中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
18期
2765-2767
,共3页
苏芬太尼%罗哌卡因%分娩%镇痛,硬膜外
囌芬太尼%囉哌卡因%分娩%鎮痛,硬膜外
소분태니%라고잡인%분면%진통,경막외
Sufentanil%Ropivacaine%Parturition%Analgesia,epidural
目的 分析不同剂量苏芬太尼联合罗哌卡因在分娩镇痛中的作用及不良反应发生情况.方法 将90例经阴道分娩的孕妇根据数字表法随机分为A组、B组和C组,各30例,均采用硬膜外麻醉.其中A组应用0.5％罗哌卡因20 ml,B组应用0.5％罗哌卡因20 ml+苏芬太尼5μg,C组应用0.5％罗哌卡因20 ml+苏芬太尼10μg.比较三组孕妇不同时点视觉模拟法(VAS)评分、改良Bromage评分、不良反应发生 率.结果 (1)用药10 min、60 min及宫口开全时,B组孕妇VAS评分均显著低于A组(t=5.5089、5.9342、4.2642,均P＜0.05),用药10 min、60 min、宫口开全及用药lh,C组孕妇VAS评分均显著低于A组(t=13.9558、6.7654、5.2154,均P＜0.05).与B组比较,C组孕妇用药10 min及60 min后VAS评分均显著降低(t=7.4353、4.2165、3.6865,均P＜0.05).(2)C组孕妇出现瘙痒的比例为26.67％,显著高于B组的3.33％及A组0(χ2=4.7059、7.0673,均P＜0.05).结论 在硬膜外分娩镇痛中,5μg苏芬太尼+0.5％罗哌卡因20ml镇痛效果好,不良反应少,可以推广应用.
目的 分析不同劑量囌芬太尼聯閤囉哌卡因在分娩鎮痛中的作用及不良反應髮生情況.方法 將90例經陰道分娩的孕婦根據數字錶法隨機分為A組、B組和C組,各30例,均採用硬膜外痳醉.其中A組應用0.5％囉哌卡因20 ml,B組應用0.5％囉哌卡因20 ml+囌芬太尼5μg,C組應用0.5％囉哌卡因20 ml+囌芬太尼10μg.比較三組孕婦不同時點視覺模擬法(VAS)評分、改良Bromage評分、不良反應髮生 率.結果 (1)用藥10 min、60 min及宮口開全時,B組孕婦VAS評分均顯著低于A組(t=5.5089、5.9342、4.2642,均P＜0.05),用藥10 min、60 min、宮口開全及用藥lh,C組孕婦VAS評分均顯著低于A組(t=13.9558、6.7654、5.2154,均P＜0.05).與B組比較,C組孕婦用藥10 min及60 min後VAS評分均顯著降低(t=7.4353、4.2165、3.6865,均P＜0.05).(2)C組孕婦齣現瘙癢的比例為26.67％,顯著高于B組的3.33％及A組0(χ2=4.7059、7.0673,均P＜0.05).結論 在硬膜外分娩鎮痛中,5μg囌芬太尼+0.5％囉哌卡因20ml鎮痛效果好,不良反應少,可以推廣應用.
목적 분석불동제량소분태니연합라고잡인재분면진통중적작용급불량반응발생정황.방법 장90례경음도분면적잉부근거수자표법수궤분위A조、B조화C조,각30례,균채용경막외마취.기중A조응용0.5％라고잡인20 ml,B조응용0.5％라고잡인20 ml+소분태니5μg,C조응용0.5％라고잡인20 ml+소분태니10μg.비교삼조잉부불동시점시각모의법(VAS)평분、개량Bromage평분、불량반응발생 솔.결과 (1)용약10 min、60 min급궁구개전시,B조잉부VAS평분균현저저우A조(t=5.5089、5.9342、4.2642,균P＜0.05),용약10 min、60 min、궁구개전급용약lh,C조잉부VAS평분균현저저우A조(t=13.9558、6.7654、5.2154,균P＜0.05).여B조비교,C조잉부용약10 min급60 min후VAS평분균현저강저(t=7.4353、4.2165、3.6865,균P＜0.05).(2)C조잉부출현소양적비례위26.67％,현저고우B조적3.33％급A조0(χ2=4.7059、7.0673,균P＜0.05).결론 재경막외분면진통중,5μg소분태니+0.5％라고잡인20ml진통효과호,불량반응소,가이추엄응용.
Objective To analyze the effect of different doses of sufentanil combined with ropivacaine in labor analgesia and its adverse events.Methods According to the digital table,90 vaginal delivery women were randomly divided into group A,groupB and group C,each group 30 cases,which all used epidural anesthesia.Group A chosen 0.5％ ropivacaine 20ml,and group B chosen 0.5％ ropivacaine tetracaine 20ml + sufentanil 5μg,and group C used 0.5％ ropivacaine 20ml + sufentanil 10μg.The visual analogue score(VAS),modified Bromage score,incidence of adverse reactions of pregnant women at different time points were compared.Results (1) At 10min,60min after medication and the cervix openning whole,the VAS scores of pregnant women in group B were significantly lower than those in group A(t =5.5089,5.9342,4.2642,all P ＜0.05),and at 10min,60min after medication,the cervix openning whole and at 1 h after medication,the VAS scores of pregnant women in group C were significantly lower than those in group A (t =13.9558,6.7654,5.2154,all P ＜ 0.05).Compared with group B,the VAS scores of pregnant women in group C at 10 min and 60 min after medication were significantly lower(t =7.4353,4.2165,3.6865,all P＜0.05).(2)The itching rate in group C (26.67％) was significantly higher than that in group B(3.33％) and group A (0) (χ2 =4.7059,7.0673,all P ＜ 0.05).Conclusion In epidural analgesia,5 μg sufentanil + 0.5 ％ ropivacaine 20ml analgesic has good effect and less adverse reactions,which can be used widely.
