心血管病防治知识（下半月）
心血管病防治知識（下半月）
심혈관병방치지식（하반월）
XINXUEGUANBING FANGZHI ZHISHI
2014年
8期
17-19
,共3页
缬沙坦氨氯地平%老年高血压%临床疗效
纈沙坦氨氯地平%老年高血壓%臨床療效
힐사탄안록지평%노년고혈압%림상료효
Valsartan and amlodipine%Elderly hypertension%Clinical efficacy
目的：研究缬沙坦氨氯地平片治疗老年高血压的临床疗效及安全性。方法抽取于2012年1月~2013年1月来我门诊部就诊的老年高血压患者110例，随机分为观察组与对照组，每组55例，观察组采用缬沙坦氨氯地平片治疗，对照组采用缬沙坦分散片治疗，12周后比较两组患者临床疗效及不良反应发生情况。结果①治疗结束后，观察组显效31例，有效20例，无效4例，总有效率为92.7%（51/55），对照组显效17例，有效26例，无效12例，总有效率为78.1%（43/55），组间差异具统计学意义（P＜0.05）；②两组患者均未发生药物不良反应，组间差异无统计学意义（P＞0.05）。结论缬沙坦氨氯地平片治疗老年高血压临床疗效确切，不良反应少，值得推广应用。
目的：研究纈沙坦氨氯地平片治療老年高血壓的臨床療效及安全性。方法抽取于2012年1月~2013年1月來我門診部就診的老年高血壓患者110例，隨機分為觀察組與對照組，每組55例，觀察組採用纈沙坦氨氯地平片治療，對照組採用纈沙坦分散片治療，12週後比較兩組患者臨床療效及不良反應髮生情況。結果①治療結束後，觀察組顯效31例，有效20例，無效4例，總有效率為92.7%（51/55），對照組顯效17例，有效26例，無效12例，總有效率為78.1%（43/55），組間差異具統計學意義（P＜0.05）；②兩組患者均未髮生藥物不良反應，組間差異無統計學意義（P＞0.05）。結論纈沙坦氨氯地平片治療老年高血壓臨床療效確切，不良反應少，值得推廣應用。
목적：연구힐사탄안록지평편치료노년고혈압적림상료효급안전성。방법추취우2012년1월~2013년1월래아문진부취진적노년고혈압환자110례，수궤분위관찰조여대조조，매조55례，관찰조채용힐사탄안록지평편치료，대조조채용힐사탄분산편치료，12주후비교량조환자림상료효급불량반응발생정황。결과①치료결속후，관찰조현효31례，유효20례，무효4례，총유효솔위92.7%（51/55），대조조현효17례，유효26례，무효12례，총유효솔위78.1%（43/55），조간차이구통계학의의（P＜0.05）；②량조환자균미발생약물불량반응，조간차이무통계학의의（P＞0.05）。결론힐사탄안록지평편치료노년고혈압림상료효학절，불량반응소，치득추엄응용。
Objective To investigate the clinical efficacy and safety of valsartan and amlodipine tablets in the treatment of elderly hypertension. Methods A total of 110 elderly patients with hypertension who visited for treatment in the outpatient department of our hospital from January 2012 to January 2013 were randomly divided into observation group and control group, with 55 cases in each group. The observation group was treated by valsartan and amlodipine tablets, while the control group was given valsartan dispersible tablets. Clinical efficacy and adverse reactions of the two groups were compared after 12 weeks of treatment. Results After treatment, 31 cases in the observation group showed marked response, 20 showed response, and 4 showed no response; the overall response rate was 92.7% (51/55). Seventeen cases in the control group showed marked response, 26 showed response, and 12 showed no response; the overall response was 78.1%(43/55). There were significant differences in treatment responses between the two groups (P<0.05). No drug-related adverse reactions were found in either group, showing no significant difference between the two groups (P>0.05). Conclusion Valsartan and amlodipine tablets are effective in the treatment of elderly hypertension with few adverse reactions and thus deserve clinical promotion.
