CAJ | 학술논문

目的：探讨纳米细菌在伴钙化和不伴钙化的乳腺恶性肿瘤与良性肿瘤患者血清与组织中的分布情况。方法将110例乳腺肿瘤患者根据良恶性及是否伴钙化分组。 A组30例恶性伴钙化，B组30例恶性无钙化，C组20例良性伴钙化，D组30例良性无钙化。 ELASA法测定各组患者血清中纳米细菌的感染情况，免疫组化法检测各组患者组织中纳米细菌的感染情况。结果 A、B、C、D各组血清中纳米细菌的感染率分别为73．3％，10．0％，5．0％，6．7％。 A、B、C、D各组组织中纳米细菌的感染率分别为93．3％，13．3％，5．0％，0．0％。 A组血清与组织中纳米细菌感染率与其他组相比，差异均有统计学意义（P＜0．01）。结论伴微钙化的乳腺癌患者血清和组织中纳米细菌感染率明显增高，提示纳米细菌可能和乳腺癌微钙化的形成相关。
목적：탐토납미세균재반개화화불반개화적유선악성종류여량성종류환자혈청여조직중적분포정황。방법장110례유선종류환자근거량악성급시부반개화분조。 A조30례악성반개화，B조30례악성무개화，C조20례량성반개화，D조30례량성무개화。 ELASA법측정각조환자혈청중납미세균적감염정황，면역조화법검측각조환자조직중납미세균적감염정황。결과 A、B、C、D각조혈청중납미세균적감염솔분별위73．3％，10．0％，5．0％，6．7％。 A、B、C、D각조조직중납미세균적감염솔분별위93．3％，13．3％，5．0％，0．0％。 A조혈청여조직중납미세균감염솔여기타조상비，차이균유통계학의의（P＜0．01）。결론반미개화적유선암환자혈청화조직중납미세균감염솔명현증고，제시납미세균가능화유선암미개화적형성상관。
Objective To explore the distribution of nanobacteria in serum and tissues of calcified and non calcified breast malignant tumors and breast benign tumors .Methods 110 patients with breast tumors were divided into 4 groups based on microcalcification and tumor types .Group A (n=30):cancer with microcalcification:Group B(n=30):cancer without microcal-cification:Group C ( n=30 ):benign tumor with microcalcification:Group D ( n=20 ):benign tumor without microcalcification . Nanobacteria in serum samples were detected by ELASA .Nanobacteria in tissue samples were detected by SABC immunohisto-chemistry (IHC).Results The nanobacterial infection rates in serum samples in Group A ,B,C and D were 73.3%,10.0%, 5.0%and 6.7%respectively.The nanobacterial infection rates in tissue samples in Group A ,B,C and D were 93.3%,13.3%, 5.0%and 0%respectively.Nanobacterial infection rates in serum and tissue samples in Group A and the rest groups had statisti -cal difference (P<0.01).Conclusion Breast cancer patients with microcalcification have a significantly elevated nanobacterial infection rate in serum and tissues compared with others ,which indicates that nanobacteria may be related to microcalcification in breast cancers .