CAJ | 학술논문

目的：探讨类风湿关节炎( RA)患者合并甲状腺疾病的发生情况和严重程度。方法回顾性研究分析我院123例RA患者,根据甲状腺功能情况分为甲状腺功能正常组和异常组,分别作为对照组和观察组,确定RA评分,并测定两组患者的甲状腺功能、TPOAb、TGAb,进行统计学分析。结果123例RA患者中有28例合并甲状腺功能异常,发生率22．8%。观察组RA评分和TPOAb、TGAb阳性率均高于对照组,且RA评分与TPOAb、TGAb呈正相关。 RA评分与甲状腺功能无相关性。结论 RA合并甲状腺功能异常应引起广大医务工作者的重视,特别是重视对RA患者完善甲状腺功能和相关抗体的筛查,从而尽早采取更积极的治疗,改善预后。
목적：탐토류풍습관절염( RA)환자합병갑상선질병적발생정황화엄중정도。방법회고성연구분석아원123례RA환자,근거갑상선공능정황분위갑상선공능정상조화이상조,분별작위대조조화관찰조,학정RA평분,병측정량조환자적갑상선공능、TPOAb、TGAb,진행통계학분석。결과123례RA환자중유28례합병갑상선공능이상,발생솔22．8%。관찰조RA평분화TPOAb、TGAb양성솔균고우대조조,차RA평분여TPOAb、TGAb정정상관。 RA평분여갑상선공능무상관성。결론 RA합병갑상선공능이상응인기엄대의무공작자적중시,특별시중시대RA환자완선갑상선공능화상관항체적사사,종이진조채취경적겁적치료,개선예후。
Objective To inquiry into the Incidence and severity of rheumatoid arthritis incorporate with thyroid disease. Method The retrospective analysis of 123 patients, were divided into the normal group and abnormal group according to thyroid function respectively, as the observation group and the control group. RA score 、thyroid function 、TPOAb and TGAb of the 123 patients were confirmed and analyzed statistically. Results Among the 123 RA patients, 28 cases with abnormal thyroid func-tion, the incidence was 22. 8%. The observation group RA score and the positive rate of TPOAb、TGAb was higher than that of the control group, RA was positively correlated with the TPOAb and TGAb score,No correlation between RA score and thyroid function. Conclusion RA patients with abnormal thyroid function should cause the attention of medical workers, especially pay attention to patients with RA improve screening thyroid function and antibodies, so as soon as possible to take more aggressive treatment, improve the prognosis.