CAJ | 학술논문

目的：探讨血清SOD、ET和NO水平在小儿支气管哮喘检测中的重要诊断价值。方法选择本院2010年1月至2013年10月收治的支气管哮喘急性发作期患儿82例,分为重度组23例,轻、中度组59例。正常对照组为在我院体检合格的健康儿童74例。放射免疫分析法( RIA)测定血清SOD和ET,采用硝酸还原酶法测定NO。结果与正常对照组比较,支气管哮喘组,支气管哮喘重度组,支气管哮喘轻、中度组的血清SOD水平显著降低,血清NO和ET水平显著升高,差异有统计学意义(P<0．05)。几者联合检测的阳性率达91．46%(P<0．05)。结论血清SOD、NO和ET可以作为诊断小儿支气管哮喘的重要指标,联合检测几者对小儿支气管哮喘具有重要的诊断价值。
목적：탐토혈청SOD、ET화NO수평재소인지기관효천검측중적중요진단개치。방법선택본원2010년1월지2013년10월수치적지기관효천급성발작기환인82례,분위중도조23례,경、중도조59례。정상대조조위재아원체검합격적건강인동74례。방사면역분석법( RIA)측정혈청SOD화ET,채용초산환원매법측정NO。결과여정상대조조비교,지기관효천조,지기관효천중도조,지기관효천경、중도조적혈청SOD수평현저강저,혈청NO화ET수평현저승고,차이유통계학의의(P<0．05)。궤자연합검측적양성솔체91．46%(P<0．05)。결론혈청SOD、NO화ET가이작위진단소인지기관효천적중요지표,연합검측궤자대소인지기관효천구유중요적진단개치。
Objective To understand the value of ET and NO levels in children with bronchial asthma detection. Meth-ods Select 82 cases with acute exacerbation of bronchial asthma between January 2010 and October 2013 in our hospital, as bronchial asthma group;and were divided into severe asthma group of 23 patients, b mild to moderate group of 59 patients. Nor-mal control group in our hospital medical qualified health care department for children 74 cases. Serum SOD , ET and No. Results Compared with normal control group, asthma group, bronchial asthma and severe group, bronchial asthma light, serum SOD levels moderate group was significantly reduced, serum NO and ET levels were significantly increased, with a significant difference (P<0. 05 ). A few were combined detection rate of 91. 46 % (P<0. 05) . Conclusion Serum SOD, NO and ET can be used as an important indicator of diagnosis in children with bronchial asthma, who have combined detection of several important diagnos-tic value in children with bronchial asthma.