临床儿科杂志
臨床兒科雜誌
림상인과잡지
2014年
8期
720-723
,共4页
沈夏梦%华春珍%王晓芳%庞福珍
瀋夏夢%華春珍%王曉芳%龐福珍
침하몽%화춘진%왕효방%방복진
肺炎支原体%肺炎%分泌型白细胞蛋白酶抑制剂%儿童
肺炎支原體%肺炎%分泌型白細胞蛋白酶抑製劑%兒童
폐염지원체%폐염%분비형백세포단백매억제제%인동
Mycoplasma pneumoniae%pneumonia%secretory leukocyte proteinase inhibitor%child
目的：分析肺炎支原体肺炎(MPP)患儿的临床特点及其血浆分泌型白细胞蛋白酶抑制剂(SLPI)水平的变化。方法比较分析136例MPP住院患儿的临床资料及血浆SLPI水平。结果136例MPP患儿中男80例、女56例，＞4岁占82.4%。有发热者92.7%，反复剧烈咳嗽83.8%，肺部曾闻及干湿啰音74.3%。所有患儿胸片均可见大片状或斑片状阴影。急性期白细胞计数降低72.1%，中性粒细胞百分数正常59.6%，超敏C反应蛋白(hs-CRP)增高63.2%。85例查急性期血浆SLPI水平为(9.3±8.8)ng/ml，恢复期为(11.8±8.0)ng/ml，差异有统计学意义(Z=3.08，P=0.002)。结论 MPP临床特点以发热、反复剧烈咳嗽、胸片见大片状或斑片状阴影为主，外周血白细胞计数不增高，中性粒细胞比例正常而hs-CRP增高。MPP患儿急性期血浆SLPI水平明显低于恢复期。
目的：分析肺炎支原體肺炎(MPP)患兒的臨床特點及其血漿分泌型白細胞蛋白酶抑製劑(SLPI)水平的變化。方法比較分析136例MPP住院患兒的臨床資料及血漿SLPI水平。結果136例MPP患兒中男80例、女56例，＞4歲佔82.4%。有髮熱者92.7%，反複劇烈咳嗽83.8%，肺部曾聞及榦濕啰音74.3%。所有患兒胸片均可見大片狀或斑片狀陰影。急性期白細胞計數降低72.1%，中性粒細胞百分數正常59.6%，超敏C反應蛋白(hs-CRP)增高63.2%。85例查急性期血漿SLPI水平為(9.3±8.8)ng/ml，恢複期為(11.8±8.0)ng/ml，差異有統計學意義(Z=3.08，P=0.002)。結論 MPP臨床特點以髮熱、反複劇烈咳嗽、胸片見大片狀或斑片狀陰影為主，外週血白細胞計數不增高，中性粒細胞比例正常而hs-CRP增高。MPP患兒急性期血漿SLPI水平明顯低于恢複期。
목적：분석폐염지원체폐염(MPP)환인적림상특점급기혈장분비형백세포단백매억제제(SLPI)수평적변화。방법비교분석136례MPP주원환인적림상자료급혈장SLPI수평。결과136례MPP환인중남80례、녀56례，＞4세점82.4%。유발열자92.7%，반복극렬해수83.8%，폐부증문급간습라음74.3%。소유환인흉편균가견대편상혹반편상음영。급성기백세포계수강저72.1%，중성립세포백분수정상59.6%，초민C반응단백(hs-CRP)증고63.2%。85례사급성기혈장SLPI수평위(9.3±8.8)ng/ml，회복기위(11.8±8.0)ng/ml，차이유통계학의의(Z=3.08，P=0.002)。결론 MPP림상특점이발열、반복극렬해수、흉편견대편상혹반편상음영위주，외주혈백세포계수불증고，중성립세포비례정상이hs-CRP증고。MPP환인급성기혈장SLPI수평명현저우회복기。
Objective To analyze the clinical features and the plasma secretory leukocyte proteinase inhibitor (SLPI) levels in children with Mycoplasma pneumoniae pneumonia (MPP). Methods Clinical data and plasma SLPI levels of 136 children with MPP were retrospectively analyzed. Results From July 2011 to June 2013,136 children (male 80, female 56) with MPP were included in the study. The onset ages of all children ranged from 11 months to 14 years (mean age, 6.2±3.0 years), and 82.4%of the cases were at the age of 4 to 14 years. One hundred and twenty six cases (92.7%) with long-last high fever, 83.8%with cough, 74.3%with rale were found in the study. Small or large patchy shadows in chest X-ray radiography were found in all the cases. At the acute phase, 72.1%with low white blood cell count, 59.6%with normal neutrophil cell and 63.2%with higher high sensitive C-reactive protein (hs-CRP) were observed. The SLPI level at the acute phase in 85 cases was (9.3±8.8) ng/ml, which was signiifcant lower than that at the convalescent phase (11.8±8.0 ng/ml, Z=3.08, P=0.002). Conclusions The clinical features of MPP are usually presented with high fever, cough, higher hs-CRP, normal or lower white blood cell and neutrophil cell count, small or large patchy shadows in chest X-ray radiography. The plasma SLPI level at the acute phase was signiifcantly lower than that in convalescent phase in children with MPP.
