国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
12期
1577-1579
,共3页
邹原方%罗婉莹%关晓东%唐杏明%梁翔%郭少卿
鄒原方%囉婉瑩%關曉東%唐杏明%樑翔%郭少卿
추원방%라완형%관효동%당행명%량상%곽소경
维持性腹膜透析%葡萄球菌%危险因素
維持性腹膜透析%葡萄毬菌%危險因素
유지성복막투석%포도구균%위험인소
continuous ambulatory peritoneal dialysis%Staphylococcus%associated factors
目的：探讨东莞地区维持性腹膜透析患者腹膜透析相关性葡萄球菌腹膜炎的发病率及其相关危险因素。方法选取中山大学附属东华医院腹膜透析中心192例患者为研究对象。根据腹膜透析液培养结果将患者分成腹膜炎组与对照组。腹膜透析相关性葡萄球菌腹膜炎相关危险因素分析采用多因素Logistic回归。结果192例患者中，共有16例（8．3％）患者发生腹膜透析相关性葡萄球菌腹膜炎，致病菌以表皮葡萄球菌为主，治愈率为81．25％，病死率为6．25％。高龄（OR＝1．35，95％CI 为1．16～7．68，P＝0．026）、糖尿病（OR＝3．34，95％CI 为1．90～6．54，P＜0．01）、低血红蛋白（OR＝1．68，95％CI 为1．21～6．48， P＝0．022）及低清蛋白血症（OR＝1．04，95％CI为1．02～1．07，P＝0．036）是腹膜透析相关性葡萄球菌腹膜炎的相关危险因素。结论东莞地区腹膜透析相关性葡萄球菌腹膜炎发病率较高，高龄、低血红蛋白、糖尿病及低清蛋白血症是其相关危险因素。
目的：探討東莞地區維持性腹膜透析患者腹膜透析相關性葡萄毬菌腹膜炎的髮病率及其相關危險因素。方法選取中山大學附屬東華醫院腹膜透析中心192例患者為研究對象。根據腹膜透析液培養結果將患者分成腹膜炎組與對照組。腹膜透析相關性葡萄毬菌腹膜炎相關危險因素分析採用多因素Logistic迴歸。結果192例患者中，共有16例（8．3％）患者髮生腹膜透析相關性葡萄毬菌腹膜炎，緻病菌以錶皮葡萄毬菌為主，治愈率為81．25％，病死率為6．25％。高齡（OR＝1．35，95％CI 為1．16～7．68，P＝0．026）、糖尿病（OR＝3．34，95％CI 為1．90～6．54，P＜0．01）、低血紅蛋白（OR＝1．68，95％CI 為1．21～6．48， P＝0．022）及低清蛋白血癥（OR＝1．04，95％CI為1．02～1．07，P＝0．036）是腹膜透析相關性葡萄毬菌腹膜炎的相關危險因素。結論東莞地區腹膜透析相關性葡萄毬菌腹膜炎髮病率較高，高齡、低血紅蛋白、糖尿病及低清蛋白血癥是其相關危險因素。
목적：탐토동완지구유지성복막투석환자복막투석상관성포도구균복막염적발병솔급기상관위험인소。방법선취중산대학부속동화의원복막투석중심192례환자위연구대상。근거복막투석액배양결과장환자분성복막염조여대조조。복막투석상관성포도구균복막염상관위험인소분석채용다인소Logistic회귀。결과192례환자중，공유16례（8．3％）환자발생복막투석상관성포도구균복막염，치병균이표피포도구균위주，치유솔위81．25％，병사솔위6．25％。고령（OR＝1．35，95％CI 위1．16～7．68，P＝0．026）、당뇨병（OR＝3．34，95％CI 위1．90～6．54，P＜0．01）、저혈홍단백（OR＝1．68，95％CI 위1．21～6．48， P＝0．022）급저청단백혈증（OR＝1．04，95％CI위1．02～1．07，P＝0．036）시복막투석상관성포도구균복막염적상관위험인소。결론동완지구복막투석상관성포도구균복막염발병솔교고，고령、저혈홍단백、당뇨병급저청단백혈증시기상관위험인소。
Objective To study the incidence and risk factors of peritoneal dialysis-related Staphylococcus peritonitis in continu-ous ambulatory peritoneal dialysis(CAPD)patients in Dongguan.Methods 192 CAPD cases with peritoneal dialysis-related perito-nitis in the Affiliated Donghua Hospital of Sun Yet-Sen University were enrolled as subjects and divided into peritonitis group and control group,according to the culture results of peritoneal dialysis fluid.The associated risk factors of peritoneal dialysis-related Staphylococcus peritonitis were investigated through Logistic regression analysis.Results The incidence of peritoneal dialysis-re-lated Staphylococcus peritonitis was 8.3%(16 cases).The main pathogens were Staphylococcus spidermidis.The cure rate was 81.25%,and the mortality was 6.25%.The advanced age(OR= 1.35,95%CI 1.16-7.68,P= 0.026),diabetes(OR= 3.34,95%CI 1.90-6.54,P<0.01),lower hemoglobin(OR= 1.68,95%CI 1.21-6.48,P= 0.022)and lower albumin(OR= 1.04,95%CI 1.02-1.07,P= 0.036)were associated risk factors of peritoneal dialysis-related Staphylococcus peritonitis.Conclusion The inci-dence of peritoneal dialysis-related Staphylococcus peritonitis is high in Dongguan,and advanced age,diabetes,lower hemoglobin and lower albumin are associated risk factors of it.
