CAJ | 학술논문

目的探讨食管癌患者放疗期间体质量下降的影响因素.方法选取102例接受放疗的食管癌患者为研究对象,收集患者放疗期间的体质量、人口学资料、饮食摄入量、疾病治疗资料、放疗副反应和安德森症状评估量表评分情况,采用多元逐步回归方法分析放疗期间患者体质量下降的影响因素.结果 102例患者放疗前后体质量下降0～5.00 kg,平均(1.64±0.69) kg.多元回归分析显示,体质量下降与能量摄入低(x1)、消化道反应(x2)、肿瘤分期(x3)和放疗剂量(x4)有关,回归方程为y=-0.182+0.142x1+0.245x2 +0.210x3 +0.605x4.结论维持能量摄入和预防消化道副反应对控制食管癌患者体质量的下降趋势至关重要.
목적 탐토식관암환자방료기간체질량하강적영향인소.방법 선취102례접수방료적식관암환자위연구대상,수집환자방료기간적체질량、인구학자료、음식섭입량、질병치료자료、방료부반응화안덕삼증상평고량표평분정황,채용다원축보회귀방법분석방료기간환자체질량하강적영향인소.결과 102례환자방료전후체질량하강0～5.00 kg,평균(1.64±0.69) kg.다원회귀분석현시,체질량하강여능량섭입저(x1)、소화도반응(x2)、종류분기(x3)화방료제량(x4)유관,회귀방정위y=-0.182+0.142x1+0.245x2 +0.210x3 +0.605x4.결론 유지능량섭입화예방소화도부반응대공제식관암환자체질량적하강추세지관중요.
Objective To identify factors associated with weight loss during radiotherapy (RT) in patients with esophageal cancer.Methods One hundred and two esophageal cancer patients who received radiotherapy were enrolled as our subjects.Patients' weight,characteristics,dietary intake,tumor and treatment data,acute adverse effects were collected.Anderson Symptom Inventory was performed.Multiple linear regression analysis was applied to identify independent factors with weight loss during RT.Results The average weight loss during RT was (1.64 ± 0.69) kg,ranged from 0 to 5.00 kg.Multiple regression analysis showed that the weight loss was associated with lower dietary energy intake (x1),digestive adverse effect (x2),TNM stage (x3) and radiation dose(x4).The regression equitation was y =-0.182 + 0.142x1 + 0.245x2 + 0.210x3 +0.605x4.Conclusion Maintaining energy intake and preventing and treating digestive adverse effects are two important measurement in esophageal cancer patients during RT.