中国保健营养(下旬刊)
中國保健營養(下旬刊)
중국보건영양(하순간)
CHINA HEALTH CARE & NUTRITION
2014年
1期
8-8
,共1页
类风湿性关节炎%抗-CCP抗体%RF
類風濕性關節炎%抗-CCP抗體%RF
류풍습성관절염%항-CCP항체%RF
Rheumatoid arthritis%Anti-CCP antibody%RF
目的:探讨抗-CCP抗体与RF检测对类风湿性关节炎( RA)的临床诊断价值。方法对51例类风湿性关节炎患者( RA组)、45例非类风湿性关节炎的自身免疫性疾病患者(非RA组)、30例健康人(对照组)进行抗-CCP抗体及RF测定,并对阳性率、灵敏度、特异性进行比较分析。结果 RA组抗-CPP抗体、RF阳性率均高于其他两组,差异具有统计学意义;抗-CCP抗体特异性明显高于RF,差异有统计学意义;二者灵敏度差异无统计学意义。结论抗-CCP抗体对类风湿性关节炎具有较好的灵敏度和很高的特异性,联合检测抗-CCP抗体和 RF可以提高诊断的准确性,利于类风湿性关节炎的早期诊断。
目的:探討抗-CCP抗體與RF檢測對類風濕性關節炎( RA)的臨床診斷價值。方法對51例類風濕性關節炎患者( RA組)、45例非類風濕性關節炎的自身免疫性疾病患者(非RA組)、30例健康人(對照組)進行抗-CCP抗體及RF測定,併對暘性率、靈敏度、特異性進行比較分析。結果 RA組抗-CPP抗體、RF暘性率均高于其他兩組,差異具有統計學意義;抗-CCP抗體特異性明顯高于RF,差異有統計學意義;二者靈敏度差異無統計學意義。結論抗-CCP抗體對類風濕性關節炎具有較好的靈敏度和很高的特異性,聯閤檢測抗-CCP抗體和 RF可以提高診斷的準確性,利于類風濕性關節炎的早期診斷。
목적:탐토항-CCP항체여RF검측대류풍습성관절염( RA)적림상진단개치。방법대51례류풍습성관절염환자( RA조)、45례비류풍습성관절염적자신면역성질병환자(비RA조)、30례건강인(대조조)진행항-CCP항체급RF측정,병대양성솔、령민도、특이성진행비교분석。결과 RA조항-CPP항체、RF양성솔균고우기타량조,차이구유통계학의의;항-CCP항체특이성명현고우RF,차이유통계학의의;이자령민도차이무통계학의의。결론항-CCP항체대류풍습성관절염구유교호적령민도화흔고적특이성,연합검측항-CCP항체화 RF가이제고진단적준학성,리우류풍습성관절염적조기진단。
Objective To investigate the anti-CCP antibody and RF in rheumatoid arthritis(RA)clinical diagnostic value.Methods 51 cases of RA patients(RA group),45 cases of autoimmune disease in patients with non RA(non RA group),30 cases of healthy(control group)were anti-CCP antibody and RF assay,and the positive rate,sensitivity,specificity,comparative analysis.Results in group RA,anti-CPP antibody,RF positive rates were higher than the other two groups ,the differ-ence was statistically significant;the specificity of anti-CCP antibody was significantly higher than that of RF ,the difference was statistically significant;no statistically significant differences in two sensitivity.Conclusion The anti-CCP antibody has good sensitivity and high specificity for RA,anti-CCP antibody and RF improve the accuracy of diagnosis can be,conducive to the early diagnosis of RA.